AGBL4, ATP/GTP binding protein like 4, 84871

N. diseases: 30; N. variants: 13
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs147247472
rs147247472
Entrez Id: 84871;100874313
Gene Symbol: AGBL4;AGBL4-IT1
AGBL4;AGBL4-IT1
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		0.710 GeneticVariation BEFREE We identified and replicated three novel loci that were associated with the common risk of heroin, methamphetamine addiction, and alcoholism: ANKS1B rs2133896 (P<sub>meta</sub> = 3.60 × 10<sup>-9</sup>), AGBL4 rs147247472 (P<sub>meta</sub> = 3.40 × 10<sup>-12</sup>), and CTNNA2 rs10196867 (P<sub>meta</sub> = 4.73 × 10<sup>-9</sup>). 31462767 2019
dbSNP: rs147247472
rs147247472
Entrez Id: 84871;100874313
Gene Symbol: AGBL4;AGBL4-IT1
AGBL4;AGBL4-IT1
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic 		A 0.710 GeneticVariation GWASCAT We identified and replicated three novel loci that were associated with the common risk of heroin, methamphetamine addiction, and alcoholism: ANKS1B rs2133896 (P<sub>meta</sub> = 3.60 × 10<sup>-9</sup>), AGBL4 rs147247472 (P<sub>meta</sub> = 3.40 × 10<sup>-12</sup>), and CTNNA2 rs10196867 (P<sub>meta</sub> = 4.73 × 10<sup>-9</sup>). 31462767 2019
dbSNP: rs1167311
rs1167311
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs12121950
rs12121950
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs12128108
rs12128108
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C0036341
Disease:
Schizophrenia 		T 0.700 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913 2019
dbSNP: rs12128108
rs12128108
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1269683
Disease:
Major Depressive Disorder 		T 0.700 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913 2019
dbSNP: rs12128108
rs12128108
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs147247472
rs147247472
Entrez Id: 84871;100874313
Gene Symbol: AGBL4;AGBL4-IT1
AGBL4;AGBL4-IT1
CUI: C0236970
Disease:
Alcohol-Induced Disorders 		A 0.700 GeneticVariation GWASCAT Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence. 31462767 2019
dbSNP: rs147247472
rs147247472
Entrez Id: 84871;100874313
Gene Symbol: AGBL4;AGBL4-IT1
AGBL4;AGBL4-IT1
CUI: C0236664
Disease:
Alcohol-Related Disorders 		A 0.700 GeneticVariation GWASCAT Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence. 31462767 2019
dbSNP: rs147247472
rs147247472
Entrez Id: 84871;100874313
Gene Symbol: AGBL4;AGBL4-IT1
AGBL4;AGBL4-IT1
CUI: C0236733
Disease:
Amphetamine-Related Disorders 		A 0.700 GeneticVariation GWASCAT Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence. 31462767 2019
dbSNP: rs147247472
rs147247472
Entrez Id: 84871;100874313
Gene Symbol: AGBL4;AGBL4-IT1
AGBL4;AGBL4-IT1
CUI: C0019337
Disease:
Heroin Dependence 		A 0.700 GeneticVariation GWASCAT Identification of novel risk loci with shared effects on alcoholism, heroin, and methamphetamine dependence. 31462767 2019
dbSNP: rs319991
rs319991
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C0201899
Disease:
Aspartate aminotransferase measurement 		0.700 GeneticVariation GWASCAT Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers. 30589442 2019
dbSNP: rs946106
rs946106
Entrez Id: 84871;100874313
Gene Symbol: AGBL4;AGBL4-IT1
AGBL4;AGBL4-IT1
CUI: C0205682
Disease:
Waist-Hip Ratio 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs11579440
rs11579440
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C0871470
Disease:
Systolic Pressure 		T 0.700 GeneticVariation GWASCAT Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. 30224653 2018
dbSNP: rs11590635
rs11590635
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C0004238
Disease:
Atrial Fibrillation 		A 0.700 GeneticVariation GWASCAT Biobank-driven genomic discovery yields new insight into atrial fibrillation biology. 30061737 2018
dbSNP: rs3127553
rs3127553
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		G 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127 2018
dbSNP: rs4582848
rs4582848
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127 2018
dbSNP: rs657452
rs657452
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127 2018
dbSNP: rs3820445
rs3820445
Entrez Id: 79656;84871
Gene Symbol: BEND5;AGBL4
BEND5;AGBL4
CUI: C0014175
Disease:
Endometriosis 		G 0.700 GeneticVariation GWASCAT New variants near RHOJ and C2, HLA-DRA region and susceptibility to endometriosis in the Polish population-The genome-wide association study. 28881265 2017
dbSNP: rs657452
rs657452
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 112 new loci for body mass index in the Japanese population. 28892062 2017
dbSNP: rs3127553
rs3127553
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 26426971 2015
dbSNP: rs3127553
rs3127553
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C0455829
Disease:
Waist Circumference 		A 0.700 GeneticVariation GWASCAT New genetic loci link adipose and insulin biology to body fat distribution. 25673412 2015
dbSNP: rs4582848
rs4582848
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 26426971 2015
dbSNP: rs657452
rs657452
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 26426971 2015
dbSNP: rs657452
rs657452
Entrez Id: 84871
Gene Symbol: AGBL4
AGBL4
CUI: C1305855
Disease:
Body mass index 		A 0.700 GeneticVariation GWASCAT Genetic studies of body mass index yield new insights for obesity biology. 25673413 2015