TNFSF14, TNF superfamily member 14, 8740

N. diseases: 143; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1077667
rs1077667
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14
CUI: C0026769
Disease:
Multiple Sclerosis 		0.810 GeneticVariation BEFREE Soluble LIGHT is an inhibitor of T-cell activation and GG carriers of rs1077667, with the highest risk for MS, had the lowest serum levels. 23037546 2013
dbSNP: rs1077667
rs1077667
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14
CUI: C0026769
Disease:
Multiple Sclerosis 		G 0.810 GeneticVariation GWASCAT Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. 24076602 2013
dbSNP: rs1077667
rs1077667
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14
CUI: C0026769
Disease:
Multiple Sclerosis 		G 0.810 GeneticVariation GWASCAT Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
dbSNP: rs1077667
rs1077667
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14
CUI: C0026769
Disease:
Multiple Sclerosis 		G 0.810 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
dbSNP: rs12461821
rs12461821
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14
CUI: C0200637
Disease:
Monocyte count procedure 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs12461821
rs12461821
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14
CUI: C0750880
Disease:
Monocyte count result 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010 2018
dbSNP: rs1077667
rs1077667
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14
CUI: C0038013
Disease:
Ankylosing spondylitis 		0.010 GeneticVariation BEFREE We found rs1077667 in LIGHT and rs2171513 in BTLA with susceptibility to AS, while 12609318 in LIGHT associate with susceptibility to AS. 29207654 2017
dbSNP: rs12609318
rs12609318
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14
CUI: C0038013
Disease:
Ankylosing spondylitis 		0.010 GeneticVariation BEFREE This study intends to explore whether the susceptibility to AS is associated with rs2171513 C>T, rs1077667 G>A in LIGHT (lymphotoxin, expressed on T lymphocytes) and rs12609318 A>G in B and T lymphocyte attenuator (BTLA) in a Chinese Han population. 29207654 2017
dbSNP: rs2291668
rs2291668
Entrez Id: 8740
Gene Symbol: TNFSF14
TNFSF14
CUI: C0279626
Disease:
Squamous cell carcinoma of esophagus 		0.010 GeneticVariation BEFREE Furthermore, significant difference in DCR3 expression in ES</span>CC tissues was found between subgroups with different 147C/T variant. 20567955 2010