Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0005910
Disease:
Body Weight
C 0.800 GeneticVariation GWASDB Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260 2009
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0005910
Disease:
Body Weight
C 0.800 GeneticVariation GWASCAT Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260 2009
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0028754
Disease:
Obesity
0.720 GeneticVariation BEFREE Of five studied variants, only two (SEC16B rs10913469, SH2B1 rs4788102) were nominally associated with indices of adiposity and obesity risk in girls and only SEC16B rs10913469 in children at puberty (p < 0·05), while no statistical associations was found for three other variants (PCSK1rs6235, KCTD15 rs29941, BAT2 rs2844479). 23121087 2013
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0028754
Disease:
Obesity
0.720 GeneticVariation GWASDB A genome-wide association meta-analysis identifies new childhood obesity loci. 22484627 2012
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0028754
Disease:
Obesity
0.720 GeneticVariation BEFREE The SNP rs10913469 in SEC16B (P=0.000012) and four SNPs (rs2867125, rs6548238, rs4854344 and rs7561317) in the TMEM18 gene (P=0.00015), all of which were in almost absolute linkage disequilibrium, were significantly associated with obesity in the Japanese population. 19851340 2009
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0455829
Disease:
Waist Circumference
0.700 GeneticVariation GWASCAT Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. 31453325 2019
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C1305855
Disease:
Body mass index
0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584 2019
dbSNP: rs506589
rs506589
Entrez Id: 89866
Gene Symbol: SEC16B
SEC16B
CUI: C1314691
Disease:
Age at menarche
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs545608
rs545608
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C1305855
Disease:
Body mass index
0.700 GeneticVariation GWASCAT Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. 31453325 2019
dbSNP: rs545608
rs545608
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis
G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese. 31417091 2019
dbSNP: rs545608
rs545608
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese. 31417091 2019
dbSNP: rs545608
rs545608
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0424621
Disease:
Body Fat Distribution
C 0.700 GeneticVariation GWASCAT Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects. 30664634 2019
dbSNP: rs591120
rs591120
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C1305855
Disease:
Body mass index
C 0.700 GeneticVariation GWASCAT Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. 29273807 2018
dbSNP: rs545608
rs545608
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C1305855
Disease:
Body mass index
C 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs591120
rs591120
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C1305855
Disease:
Body mass index
C 0.700 GeneticVariation GWASCAT The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 26426971 2015
dbSNP: rs591120
rs591120
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0005893
Disease:
Body mass index procedure
C 0.700 GeneticVariation GWASDB Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. 23669352 2013
dbSNP: rs591120
rs591120
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0578022
Disease:
Finding of body mass index
C 0.700 GeneticVariation GWASDB Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course. 23669352 2013
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C1314691
Disease:
Age at menarche
C 0.700 GeneticVariation GWASDB Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. 21102462 2010
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C1305855
Disease:
Body mass index
C 0.700 GeneticVariation GWASCAT Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260 2009
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0578022
Disease:
Finding of body mass index
C 0.700 GeneticVariation GWASDB Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260 2009
dbSNP: rs10913469
rs10913469
Entrez Id: 89866;111240474
Gene Symbol: SEC16B;CRYZL2P-SEC16B
SEC16B;CRYZL2P-SEC16B
CUI: C0005893
Disease:
Body mass index procedure
C 0.700 GeneticVariation GWASDB Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260 2009