Disease: Skin toxicity ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2231137
rs2231137
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
CUI: C1167791
Disease:
Skin toxicity 		0.010 GeneticVariation BEFREE While the ABCG2 C421A polymorphism might not be a reliable marker of gefitinib-related toxicity, the ABCG2 G34A genotype may be predictive of the skin toxicity of gefitinib in NSCLC patients. 29440914 2018
dbSNP: rs2231142
rs2231142
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
CUI: C1167791
Disease:
Skin toxicity 		0.010 GeneticVariation BEFREE A dominant model showed that there was no significant association between the ABCG2 C421A polymorphism and the risk of gefitinib-induced toxicity, while the ABCG2 G34A polymorphism might be associated with an increased risk of skin toxicity in gefitinib therapy (relative risk =1.54, 95% CI 1.08-2.21, <i>P</i>=0.02). 29440914 2018