Disease: Liver diseases ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs35724
rs35724
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
CUI: C0023895
Disease:
Liver diseases 		0.010 GeneticVariation BEFREE In contrast, n = 267 (66.4%) patients harbored minor rs35724 allele (G/C or C/C) and had more advanced liver disease, as indicated by a higher model of end-stage liver disease (11 ± 4 vs 10 ± 3, P = 0.016), while other baseline characteristics were similar across FXR-SNP genotypes. 31062417 2019
dbSNP: rs56163822
rs56163822
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
CUI: C0023895
Disease:
Liver diseases 		0.010 GeneticVariation BEFREE Only 19 patients (4.7%) harbored a rs56163822 T-allele and had less pronounced liver disease as indicated by lower Child-Pugh score (CPS, 6 ± 1 vs 7 ± 2 points, P = 0.034) and higher albumin levels (38.9 ± 4.9 vs 35.9 ± 5.9 g/L, P = 0.026). 31062417 2019