rs1050274678, SLC19A1

N. diseases: 3
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Leukopenia
CUI: C0023530
Disease: Leukopenia
0.010 GeneticVariation BEFREE Meta-analysis showed east-Asian patients expressing SLCO1B1 521T>C or 1118G>A to have a two- to fourfold increased risk of irinotecan-induced neutropenia but not diarrhea. 27380948 2016
Diarrhea
CUI: C0011991
Disease: Diarrhea
0.010 GeneticVariation BEFREE Meta-analysis showed east-Asian patients expressing SLCO1B1 521T>C or 1118G>A to have a two- to fourfold increased risk of irinotecan-induced neutropenia but not diarrhea. 27380948 2016
Neutropenia
CUI: C0027947
Disease: Neutropenia
0.010 GeneticVariation BEFREE Meta-analysis showed east-Asian patients expressing SLCO1B1 521T>C or 1118G>A to have a two- to fourfold increased risk of irinotecan-induced neutropenia but not diarrhea. 27380948 2016