|
Crohn Disease
|
|
0.850 |
GeneticVariation
|
BEFREE |
Additionally, rs10758669</span> and rs2293152 in Crohn's disease and rs8074524, rs3816769, and rs10758669 in ulcerative colitis were associated with the requirement of immunsuppression.
|
27852544 |
2016 |
|
Crohn Disease
|
|
0.850 |
GeneticVariation
|
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Crohn Disease
|
|
0.850 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that JAK2 rs10758669 polymorphism was a risk factor both for CD and UC, especially in Caucasian.
|
24385239 |
2014 |
|
Crohn Disease
|
|
0.850 |
GeneticVariation
|
BEFREE |
Here, we studied the susceptibility nature of three components of IL23 signalling and Th17 cell differentiation: JAK2 rs10758669, STAT3 rs744166 and CCR6 rs2301436 initially associated with CD in Hungarian CD and UC patients.
|
22269120 |
2012 |
|
Crohn Disease
|
|
0.850 |
GeneticVariation
|
BEFREE |
JAK2 rs10758669 and STAT3 rs744166 increase susceptibility for CD.
|
22065112 |
2012 |
|
Crohn Disease
|
|
0.850 |
GeneticVariation
|
BEFREE |
For the JAK2 rs10758669 polymorphism, the homozygous C/C or heterozygous A/C genotypes increased the risk of having CD as compared with the homozygous A/A (OR=1.76, 95% CI=1.26-2.45 and OR=2.36, 95% CI=1.44-3.86, respectively, p=0.0003).
|
20109474 |
2010 |
|
Crohn Disease
|
|
0.850 |
GeneticVariation
|
GWASCAT |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
|
Crohn Disease
|
|
0.850 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
|
Crohn Disease
|
|
0.850 |
GeneticVariation
|
GWASDB |
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
|
18587394 |
2008 |
|
Crohn Disease
|
|
0.850 |
GeneticVariation
|
GWASCAT |
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
|
18587394 |
2008 |
|
Ulcerative Colitis
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Ulcerative Colitis
|
|
0.830 |
GeneticVariation
|
BEFREE |
Additionally, rs10758669</span> and rs2293152 in Crohn's disease and rs8074524, rs3816769, and r</span>s10758669 in ulcerative colitis were associated with the requirement of immunsuppression.
|
27852544 |
2016 |
|
Ulcerative Colitis
|
|
0.830 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that JAK2 rs10758669 polymorphism was a risk factor both for CD and UC, especially in Caucasian.
|
24385239 |
2014 |
|
Ulcerative Colitis
|
|
0.830 |
GeneticVariation
|
BEFREE |
Our data confirm the association between JAK2 rs10758669 (p = 0.026, OR = 1.25, 95% CI = 1.04-1.50) and STAT3 rs744166 (p = 0.04, OR = 0.83, 95% CI = 0.688-0.998) with CD, but not UC.
|
22065112 |
2012 |
|
Ulcerative Colitis
|
|
0.830 |
GeneticVariation
|
GWASDB |
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
|
21297633 |
2011 |
|
Ulcerative Colitis
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
|
21297633 |
2011 |
|
Ulcerative Colitis
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
|
20228799 |
2010 |
|
Ulcerative Colitis
|
|
0.830 |
GeneticVariation
|
GWASDB |
Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
|
20228799 |
2010 |
|
Inflammatory Bowel Diseases
|
|
0.810 |
GeneticVariation
|
BEFREE |
Macrophages from controls and ulcerative colitis patients carrying the IBD-risk rs10758669 CC genotype showed increased JAK2 expression and nucleotide-binding oligomerization domain 2-induced JAK2 phosphorylation relative to AA carriers.
|
27664279 |
2016 |
|
Inflammatory Bowel Diseases
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
23128233 |
2012 |
|
Inflammatory Bowel Diseases
|
|
0.810 |
GeneticVariation
|
GWASDB |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
23128233 |
2012 |
|
Cholangitis, Sclerosing
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Psoriasis
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Ankylosing spondylitis
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
|
Asthma
|
|
0.700 |
GeneticVariation
|
GWASDB |
Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.
|
21150878 |
2011 |