rs10853728, None

N. diseases: 5
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.020 GeneticVariation BEFREE Four SNPs were significantly associated with spontaneous HCV clearance: rs8099917 TT (vs GT), rs8105790 TT (vs CT), rs12980275 AA (vs AG) and rs10853728 CC (vs CG or GG) with OR (95% CI) 15.27 (2.07-112.50), 14.88 (2.02-109.72), 7.92 (1.88-33.32) and 2.32 (1.22-4.42) respectively. 22329371 2012
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.020 GeneticVariation BEFREE The rs10853728 genotype did not predict RVR or SVR in HCV-2 p</span>atients. 21254157 2011
Complete atrioventricular block
CUI: C0151517
Disease: Complete atrioventricular block
0.010 GeneticVariation BEFREE HBV viral load and IL28B rs10853728 CC genotype correlated with hepatitis activity in HBeAg-positive and HBeAg-negative CHB, respectively. 23469142 2013
Hepatitis
CUI: C0019158
Disease: Hepatitis
0.010 GeneticVariation BEFREE HBV viral load and IL28B rs10853728 CC genotype correlated with hepatitis activity in HBeAg-positive and HBeAg-negative CHB, respectively. 23469142 2013
Hepatitis B
CUI: C0019163
Disease: Hepatitis B
0.010 GeneticVariation BEFREE In multivariate analysis, high viral load (HBV DNA >10(8) IU/mL, p = 0.042, odds ratio = 3.946) was significantly associated with HBeAg-positive hepatitis, whereas rs10853728 CC genotype (p = 0.019, odds ratio = 3.927) was the only independent factor associated with active hepatitis in HBeAg-negative population. 23469142 2013
Hepatitis A
CUI: C0019159
Disease: Hepatitis A
0.010 GeneticVariation BEFREE HBV viral load and IL28B rs10853728 CC genotype correlated with hepatitis activity in HBeAg-positive and HBeAg-negative CHB, respectively. 23469142 2013