|
Chronic osteomyelitis
|
|
0.700 |
GeneticVariation
|
CLINVAR |
|
|
|
|
Chronic Lymphocytic Leukemia
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
|
24292274 |
2014 |
|
Chronic Lymphocytic Leukemia
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
|
24292274 |
2014 |
|
Small Lymphocytic Lymphoma
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
|
24292274 |
2014 |
|
Colorectal Carcinoma
|
|
0.840 |
GeneticVariation
|
BEFREE |
Additionally, our GWAS confirmed the previously reported association with CRC of five SNPs located at 3q36.2 (rs10936599), 8q24 (rs10505477), 8q24.21(rs6983267), 11q13.4 (rs3824999) and 14q22.2 (rs4444235).
|
24978480 |
2014 |
|
Renal Cell Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
As a sensitivity analysis, we excluded two telomere length variants in linkage disequilibrium (R<sup>2</sup>>0.5) with GWAS-identified RCC risk variants (rs10936599 and rs9420907) from the telomere length GRS; despite this exclusion, a statistically significant association between the GRS and RCC risk persisted (OR=1.73, 95% CI=1.36-2.21, p<0.0001).
|
28797570 |
2017 |
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
As a sensitivity analysis, we excluded two telomere length variants in linkage disequilibrium (R<sup>2</sup>>0.5) with GWAS-identified RCC risk variants (rs10936599 and rs9420907) from the telomere length GRS; despite this exclusion, a statistically significant association between the GRS and RCC risk persisted (OR=1.73, 95% CI=1.36-2.21, p<0.0001).
|
28797570 |
2017 |
|
Malignant neoplasm of urinary bladder
|
|
0.720 |
GeneticVariation
|
BEFREE |
At the end of the study, we suggested that there may exist an association between a combination of MYNN rs10936599 and TERC rs2293607 polymorphisms and development of bladder cancer in Turkish population.
|
30120764 |
2019 |
|
Carcinoma of bladder
|
|
0.720 |
GeneticVariation
|
BEFREE |
At the end of the study, we suggested that there may exist an association between a combination of MYNN rs10936599 and TERC rs2293607 polymorphisms and development of bladder cancer in Turkish population.
|
30120764 |
2019 |
|
Bladder Neoplasm
|
|
0.020 |
GeneticVariation
|
BEFREE |
At the end of the study, we suggested that there may exist an association between a combination of MYNN rs10936599 and TERC rs2293607 polymorphisms and development of bladder cancer in Turkish population.
|
30120764 |
2019 |
|
Multiple Myeloma
|
|
0.810 |
GeneticVariation
|
BEFREE |
Common single-nucleotide polymorphisms (SNPs) at 2p23.3 (rs6746082), 3p22.1 (rs1052501), 3q26.2 (rs10936599), 6p21.33 (rs2285803), 7p15.3 (rs4487645), 17p11.2 (rs4273077), and 22q13.1 (rs877529) have recently been shown to influence MM risk.
|
24449210 |
2014 |
|
Multiple Myeloma
|
|
0.810 |
GeneticVariation
|
GWASDB |
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.
|
23955597 |
2013 |
|
Multiple Myeloma
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.
|
23955597 |
2013 |
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Genetic predisposition to advanced biological ageing, as assayed using rs10936599, predicted a small, but significant, increased risk for childhood-onset recurrent MDD.
|
28233563 |
2017 |
|
Multiple Sclerosis
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
|
21833088 |
2011 |
|
Multiple Sclerosis
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
|
21833088 |
2011 |
|
Malignant neoplasm of urinary bladder
|
|
0.720 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies multiple loci associated with bladder cancer risk.
|
24163127 |
2014 |
|
Carcinoma of bladder
|
|
0.720 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies multiple loci associated with bladder cancer risk.
|
24163127 |
2014 |
|
Lung Diseases, Interstitial
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.
|
23583980 |
2013 |
|
Ischemic stroke
|
|
0.010 |
GeneticVariation
|
BEFREE |
In allele association analysis, allele "C" in rs10936599 of TERC gene and allele "G" in rs2853677 of TERT gene were found to have an increased risk of IS when compared with allele "T" and "A", respectively.
|
28057933 |
2017 |
|
Colorectal Carcinoma
|
|
0.840 |
GeneticVariation
|
BEFREE |
It was independently found that the same rs10936599 allele was associated with increased risk of both CRC and colorectal adenomas.
|
21708826 |
2012 |
|
Adenoma of large intestine
|
|
0.010 |
GeneticVariation
|
BEFREE |
It was independently found that the same rs10936599 allele was associated with increased risk of both CRC and colorectal adenomas.
|
21708826 |
2012 |
|
Malignant tumor of colon
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.
|
20972440 |
2010 |
|
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.
|
20972440 |
2010 |
|
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.
|
20972440 |
2010 |