rs11172113, LRP1

N. diseases: 10
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation BEFREE To further check if these variants differ by ethnicity, three single nucleotide polymorphisms (SNPs) (rs4379368, rs10504861and rs11172113) were genotyped here to find association with migraine susceptibility from North Indian population. 31505242 2019
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation GWASCAT Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. 27322543 2016
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation BEFREE To further replicate the GWAS findings, we investigated the 3 variants rs2651899 (1p36.32, PRDM16), rs10166942 (2q37.1, TRPM8), and rs11172113 (12q13.3, LRP1) for their association with migraine in the Chinese Han population. 24666033 2014
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation BEFREE We report significant influence of rs1835740, LRP1 rs11172113 and PRDM16 rs2651899 polymorphisms on migraine susceptibility in the North Indian population. 24266335 2014
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation BEFREE The meta-analysis confirmed the previous three genome-wide significant associated SNPs (rs2651899, rs10166942 and rs11172113</span>) to confer risk of migraine. 23294458 2013
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation GWASCAT Genome-wide meta-analysis identifies new susceptibility loci for migraine. 23793025 2013
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation GWASDB Genome-wide meta-analysis identifies new susceptibility loci for migraine. 23793025 2013
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation GWASCAT Genome-wide association analysis identifies susceptibility loci for migraine without aura. 22683712 2012
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation GWASDB Genome-wide association analysis identifies susceptibility loci for migraine without aura. 22683712 2012
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation BEFREE In a population-based genome-wide analysis including 5,122 migraineurs and 18,108 non-migraineurs, rs2651899 (1p36.32, PRDM16), rs10166942 (2q37.1, TRPM8) and rs11172113 (12q13.3, LRP1) were among the top seven associations (P < 5 × 10(-6)) with migraine. 21666692 2011
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation GWASCAT In a population-based genome-wide analysis including 5,122 migraineurs and 18,108 non-migraineurs, rs2651899 (1p36.32, PRDM16), rs10166942 (2q37.1, TRPM8) and rs11172113 (12q13.3, LRP1) were among the top seven associations (P < 5 × 10(-6)) with migraine. 21666692 2011
Migraine Disorders
CUI: C0149931
Disease: Migraine Disorders
0.850 GeneticVariation GWASDB In a population-based genome-wide analysis including 5,122 migraineurs and 18,108 non-migraineurs, rs2651899 (1p36.32, PRDM16), rs10166942 (2q37.1, TRPM8) and rs11172113 (12q13.3, LRP1) were among the top seven associations (P < 5 × 10(-6)) with migraine. 21666692 2011
Common Migraine
CUI: C0338480
Disease: Common Migraine
0.800 GeneticVariation GWASCAT Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. 27322543 2016
Common Migraine
CUI: C0338480
Disease: Common Migraine
0.800 GeneticVariation GWASDB Genome-wide meta-analysis identifies new susceptibility loci for migraine. 23793025 2013
peak expiratory flow (procedure)
CUI: C1518922
Disease: peak expiratory flow (procedure)
0.700 GeneticVariation GWASCAT New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. 30804560 2019
Headache
CUI: C0018681
Disease: Headache
0.700 GeneticVariation GWASCAT A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773). 29397368 2018
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.700 GeneticVariation GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
Respiratory Function Tests
CUI: C0035227
Disease: Respiratory Function Tests
0.700 GeneticVariation GWASCAT Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. 21946350 2011
Pulmonary function (finding)
CUI: C3160731
Disease: Pulmonary function (finding)
0.700 GeneticVariation GWASDB Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. 21946350 2011
Pulmonary function
CUI: C0231921
Disease: Pulmonary function
0.700 GeneticVariation GWASDB Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. 21946350 2011
Cerebrovascular accident
CUI: C0038454
Disease: Cerebrovascular accident
0.010 GeneticVariation BEFREE In the African American series, LRP1 rs11172113 was associated with an increased risk of stroke (OR 1.89, P = 0.006). 26031789 2015
Migraine with Aura
CUI: C0154723
Disease: Migraine with Aura
0.010 GeneticVariation BEFREE Five loci met stringent significance for association with migraine, among which four were selective for sub-classified migraine, including rs11172113 (LRP1) for MO. 24852292 2014