|
Sleep Apnea, Obstructive
|
|
0.010 |
GeneticVariation
|
BEFREE |
The study was conducted to investigate the association of CRP rs1130864 (1444C/T), IL-6 rs1800795 (-174G/C) and LEPR rs1137101 (Q223R) genes with OSA and NAFLD in Asian Indians residing in North India.
|
30001365 |
2018 |
|
Ischemic stroke
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our study indicates that SNP rs1130864 in the CRP gene is an independent predictor of 3-month functional outcome in patients with first-onset IS in a Han Chinese population.
|
23980698 |
2014 |
|
Post-Traumatic Stress Disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
One SNP within the CRP gene, rs1130864, was significantly associated with increased PTSD symptoms (N=2,692), including "being overly alert" as the most significant individual symptom (N=2,698).
|
25827033 |
2015 |
|
Adenoma of large intestine
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated the inter-relationships of serum levels of the inflammatory proteins CRP and in IL-6, single nucleotide polymorphisms (SNPs) in the CRP (rs1205, rs1130864, rs1800947) and IL6 (rs1800795) genes, and lifestyle factors with colorectal adenoma in a sigmoidoscopy-based case-control study of 271 adenoma cases and 539 age-, sex-, and race/ethnicity-matched controls in Hawaii.
|
20333461 |
2010 |
|
Lupus Erythematosus, Discoid
|
|
0.010 |
GeneticVariation
|
BEFREE |
Four of the polymorphisms showed differences between patients and controls. rs3093061 polymorphism was associated with a lower risk of developing lupus principally in the codominant 2 (OR = 0.219, 95% CI 0.108-0.785, P = 0.015) model. rs1130864 was associated with decreased risk mainly under codominant 1 (OR = 0.288, 95% CI 0.143-0.581, P = 0.001) model. rs1205 was associated under the over-dominant model (OR = 0.504, 95% CI 0.270-0.942, P = 0.032).
|
29556849 |
2018 |
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
We analysed the association between three genetic polymorphisms (PM) (-717C>T, rs2794521; +1059G>C, rs1800947; +1444C>T, rs1130864) at the C-reactive protein locus and related haplotypes with both circulating C-reactive protein and angiographic coronary artery disease (CAD).
|
18499652 |
2009 |
|
Endometrial Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The current results suggested that, in the Chinese population that was studied, obesity-related insulin resistance and proinflammatory effects may play an important role in endometrial cancer risk, and these effects were modified significantly by the CRP SNP rs1130864.
|
18383516 |
2008 |
|
Geographic Atrophy
|
|
0.010 |
GeneticVariation
|
BEFREE |
For geographic atrophy, rs1205 had an OR of 0.91 (95% CI, 0.74-1.13) and rs1130864 had an OR of 0.94 (95% CI, 0.76-1.16).
|
28750115 |
2017 |
|
Thyroid Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, the CRP rs1130864 A allele carrier state was significantly more frequent: (i) in BD patients with thyroid disorders than in those without (pc = 0.046), especially among females (pc = 0.01) and independently of lithium treatment, (ii) in BD patients with rapid cycling than in those without (pc = 0.004).
|
29352395 |
2018 |