|
Interleukin 1 Beta Measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation.
|
30206230 |
2018 |
|
Chronic Periodontitis
|
|
0.040 |
GeneticVariation
|
BEFREE |
We found that the statistically significant association of IL1A-889C/T (rs1800587), IL1B -31C/T (rs1143627), IL1B -511A/G (rs16944) and IL1B + 3954C/T (rs1143634) gene polymorphisms with increased susceptibility of chronic periodontitis.
|
30939298 |
2019 |
|
Chronic Periodontitis
|
|
0.040 |
GeneticVariation
|
BEFREE |
This meta-analysis in 9376 participants with 54 case/control studies revealed the rs1143634 polymorphism was associated with elevated risk of chronic periodontitis in overall analysis as well as Caucasian and Asian ethnicities and Mixed population.
|
29783069 |
2018 |
|
Chronic Periodontitis
|
|
0.040 |
GeneticVariation
|
BEFREE |
In conclusion, literature review suggests that for IL1B SNP rs1143634, EARR and CP have an opposite genetic profile.
|
30142580 |
2018 |
|
Chronic Periodontitis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Although the present results do not support that IL-1B (rs1143634) SNP could be identified as a risk predictor for CP in the present population, the synergistic interaction of the CT/CC genotypes of NLRP3 (rs4612666) SNP with ageing and/or smoking habit potentially might play a significant role in the pathogenic pathways of periodontal disease.
|
26854620 |
2016 |
|
Malignant neoplasm of breast
|
|
0.030 |
GeneticVariation
|
BEFREE |
Response to commentary article: "The association between Interleukin-1β gene rs1143634 polymorphism and the risk of breast cancer by Bei Wang, Fenlai Yuan".
|
30075887 |
2019 |
|
Breast Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Response to commentary article: "The association between Interleukin-1β gene rs1143634 polymorphism and the risk of breast cancer by Bei Wang, Fenlai Yuan".
|
30075887 |
2019 |
|
Periodontal Diseases
|
|
0.030 |
GeneticVariation
|
BEFREE |
The results of this study suggest there is no association between IL-1ß rs1143634 and rs16944 polymorphisms and PD.
|
30445239 |
2019 |
|
Malignant neoplasm of breast
|
|
0.030 |
GeneticVariation
|
BEFREE |
The association between interleukin-1β gene rs1143634 polymorphism and the risk of breast cancer.
|
30075885 |
2019 |
|
Breast Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
The association between interleukin-1β gene rs1143634 polymorphism and the risk of breast cancer.
|
30075885 |
2019 |
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Stratified analyses revealed the IL-1B gene rs1143623 and rs1143634 polymorphisms decreased the risk of CR</span>C among females, smokers and drinkers.
|
30563955 |
2018 |
|
Periodontal Diseases
|
|
0.030 |
GeneticVariation
|
BEFREE |
Although the present results do not support that IL-1B (rs1143634) SNP could be identified as a risk predictor for CP in the present population, the synergistic interaction of the CT/CC genotypes of NLRP3 (rs4612666) SNP with ageing and/or smoking habit potentially might play a significant role in the pathogenic pathways of periodontal disease.
|
26854620 |
2016 |
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
We found that rs1143634 in the interleukin-1β (IL1B) gene and rs1800871 in the interleukin-10 (IL10) gene were associated with increased risk for CRC in the Han Chinese.
|
24557062 |
2015 |
|
Periodontal Diseases
|
|
0.030 |
GeneticVariation
|
BEFREE |
No evident relationships were observed between SNP rs1800587 or rs1143634 and periodontal disease.
|
24460370 |
2014 |
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
We investigated whether IL-1B -511C>T (rs16944), IL-1B +3954C>T (rs1143634) and IL1-RN +2018T>C (rs419598) cytokine polymorphisms are correlated with colorectal cancer.
|
23192617 |
2013 |
|
Breast Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Mutant allele and genotype at IL-1β [+3954 C>T (rs1143634)] site associated with increased BC risk, while mutant allele and genotypes at IL-6 [-174 G>C (rs1800795)] polymorphism appeared to be protective.
|
22818022 |
2012 |
|
Malignant neoplasm of breast
|
|
0.030 |
GeneticVariation
|
BEFREE |
Mutant allele and genotype at IL-1β [+3954 C>T (rs1143634)] site associated with increased BC risk, while mutant allele and genotypes at IL-6 [-174 G>C (rs1800795)] polymorphism appeared to be protective.
|
22818022 |
2012 |
|
Graves Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Also in the exon 5 (rs1143634), a significant increase in frequency of the C/C homozygous genotype (P = 0.001; OR = 0.18, 95% CI = 0.11-0.30) and C allele (P = 0.001; OR = 0.31, 95% CI = 0.20-0.48) was observed in GD cases as against controls.
|
29454070 |
2018 |
|
Infective endocarditis
|
|
0.020 |
GeneticVariation
|
BEFREE |
We found that the G/A genotype of the rs1143634 polymorphism within the <i>IL1B</i> gene, the G/T genotype of the rs3212227 polymorphism within the <i>IL12B</i> gene, the A/G genotype of the rs1130864 polymorphism within the <i>CRP</i> gene, and the G allele of the rs1801197 polymorphism within the <i>CALCR</i> gene were associated with a decreased risk of IE whereas the T/T genotype of the rs1205 polymorphism within the <i>CRP</i> gene was associated with a higher risk of IE.
|
28659664 |
2017 |
|
Bacterial Endocarditis
|
|
0.020 |
GeneticVariation
|
BEFREE |
We found that the G/A genotype of the rs1143634 polymorphism within the <i>IL1B</i> gene, the G/T genotype of the rs3212227 polymorphism within the <i>IL12B</i> gene, the A/G genotype of the rs1130864 polymorphism within the <i>CRP</i> gene, and the G allele of the rs1801197 polymorphism within the <i>CALCR</i> gene were associated with a decreased risk of IE whereas the T/T genotype of the rs1205 polymorphism within the <i>CRP</i> gene was associated with a higher risk of IE.
|
28659664 |
2017 |
|
Acute pancreatitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Multivariate regression analyses showed that subjects carrying the rs1143634 TT genotype had a significantly increased risk of acute pancreatitis, with an adjusted odds ratio (95% confidence interval) of 2.11 (1.03-4.51).
|
25730036 |
2015 |
|
Carcinoma of lung
|
|
0.020 |
GeneticVariation
|
BEFREE |
CART analyses did not yield a tree structure for overall survival; separate CART tree structures were identified for recurrence, based on three SNPs (IL13:rs1881457, IL1B:rs1143634, and IL12A:rs662959), and for disease-free survival, based on two SNPs (IL12A:rs662959 and IL16:rs7170924), which may suggest that these candidate IL SNPs have a specific impact on lung cancer progression and recurrence.
|
25597281 |
2015 |
|
Malignant neoplasm of lung
|
|
0.020 |
GeneticVariation
|
BEFREE |
CART analyses did not yield a tree structure for overall survival; separate CART tree structures were identified for recurrence, based on three SNPs (IL13:rs1881457, IL1B:rs1143634, and IL12A:rs662959), and for disease-free survival, based on two SNPs (IL12A:rs662959 and IL16:rs7170924), which may suggest that these candidate IL SNPs have a specific impact on lung cancer progression and recurrence.
|
25597281 |
2015 |
|
Primary malignant neoplasm of lung
|
|
0.020 |
GeneticVariation
|
BEFREE |
CART analyses did not yield a tree structure for overall survival; separate CART tree structures were identified for recurrence, based on three SNPs (IL13:rs1881457, IL1B:rs1143634, and IL12A:rs662959), and for disease-free survival, based on two SNPs (IL12A:rs662959 and IL16:rs7170924), which may suggest that these candidate IL SNPs have a specific impact on lung cancer progression and recurrence.
|
25597281 |
2015 |
|
Infective endocarditis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Additionally, we detected a potential relation between interleukin-1β c.315C>T and IE.
|
25299518 |
2014 |