Coronary heart disease
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
|
21378990 |
2011 |
Coronary heart disease
|
|
0.810 |
GeneticVariation
|
GWASDB |
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
|
21378990 |
2011 |
Coronary heart disease
|
|
0.810 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric analysis identifies novel variants for coronary artery disease.
|
21966275 |
2011 |
Coronary heart disease
|
|
0.810 |
GeneticVariation
|
GWASDB |
A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex.
|
22319020 |
2012 |
CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT, 1
|
|
0.700 |
GeneticVariation
|
GWASDB |
Large-scale association analysis identifies new risk loci for coronary artery disease.
|
23202125 |
2013 |
Coronary Artery Disease
|
|
0.840 |
GeneticVariation
|
GWASDB |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
|
24262325 |
2014 |
Coronary heart disease
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
|
24262325 |
2014 |
Cerebrovascular accident
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
|
24262325 |
2014 |
Coronary Artery Disease
|
|
0.840 |
GeneticVariation
|
BEFREE |
A recent meta-analysis has described the ZC3HC1 rs11556924 polymorphism as one of the most important signals associated with coronary artery disease (CAD) in non-rheumatic Caucasian individuals.
|
24286297 |
2013 |
Arteriosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our results indicate that ZC3HC1 rs11556924 polymorphism is associated with subclinical atherosclerosis in RA.
|
24286297 |
2013 |
Atherosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our results indicate that ZC3HC1 rs11556924 polymorphism is associated with subclinical atherosclerosis in RA.
|
24286297 |
2013 |
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results indicate that ZC3HC1 rs11556924 polymorphism is associated with subclinical atherosclerosis in RA.
|
24286297 |
2013 |
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
A subpopulation that had available follow-up data from ages of 40, 45, and 50 years was also analyzed.ZC3HC1 rs11556924 (C > T) genotype CC was associated with hypertension compared with the T-allele carriers (P = 0.013).
|
26266351 |
2015 |
Essential Hypertension
|
|
0.010 |
GeneticVariation
|
BEFREE |
Its major TT-genotype was associated with higher total cholesterol (P = 0.044) and LDL (P = 0.029) compared with the C-allele.We report for the first time that ZC3HC1 rs11556924 was associated with essential hypertension in 50-year-old patients.
|
26266351 |
2015 |
Coronary Artery Disease
|
|
0.840 |
GeneticVariation
|
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |
Myocardial Infarction
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.
|
26343387 |
2015 |
Coronary Artery Disease
|
|
0.840 |
GeneticVariation
|
BEFREE |
The CAD-associated locus 7q32.2 is unusual in that the lead variant, rs11556924, is not in strong linkage disequilibrium with any other variant and introduces a coding change in ZC3HC1, which encodes NIPA.
|
27226629 |
2016 |
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
|
27618452 |
2016 |
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
|
27618452 |
2016 |
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.
|
27841878 |
2017 |
Platelet Count measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Blood basophil count (lab test)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
Coronary Artery Disease
|
|
0.840 |
GeneticVariation
|
BEFREE |
These findings extend the genetic association between rs11556924 and coronary artery disease risk by characterizing its effects on the encoded protein, NIPA.
|
28115489 |
2017 |
Coronary heart disease
|
|
0.810 |
GeneticVariation
|
BEFREE |
These findings extend the genetic association between rs11556924 and coronary artery disease risk by characterizing its effects on the encoded protein, NIPA.
|
28115489 |
2017 |
Arteriosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The resulting amino acid change Arg363His is associated with increased expression and nuclear mobility, as well as lower rates of cell growth in HeLa cells, further supporting a role for cell proliferation in atherosclerosis and its clinical consequences.
|
28115489 |
2017 |