rs11605924, CRY2

N. diseases: 5
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Fasting blood glucose measurement
CUI: C0428568
Disease: Fasting blood glucose measurement
0.800 GeneticVariation GWASCAT Pleiotropy informed adaptive association test of multiple traits using genome-wide association study summary data. 31021400 2019
Fasting blood glucose measurement
CUI: C0428568
Disease: Fasting blood glucose measurement
0.800 GeneticVariation GWASCAT A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. 22581228 2012
Fasting blood glucose measurement
CUI: C0428568
Disease: Fasting blood glucose measurement
0.800 GeneticVariation GWASDB Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. 22885924 2012
Body mass index
CUI: C1305855
Disease: Body mass index
0.800 GeneticVariation GWASDB A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. 22581228 2012
Body mass index
CUI: C1305855
Disease: Body mass index
0.800 GeneticVariation GWASCAT A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. 22581228 2012
Fasting blood glucose measurement
CUI: C0428568
Disease: Fasting blood glucose measurement
0.800 GeneticVariation GWASCAT New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. 20081858 2010
Fasting blood sugar result
CUI: C1261430
Disease: Fasting blood sugar result
0.700 GeneticVariation GWASDB Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. 22885924 2012
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.020 GeneticVariation BEFREE The T2D risk SNP rs11605924 in the CRY2 gene was associated with increased GDM risk in Scandinavian but decreased GDM risk in Punjabi Indian women. 30919529 2019
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.020 GeneticVariation BEFREE Notably, T2D risk alleles of the variant rs1552224 near CENTD2, rs11708067 in ADCY5 and rs11605924 in CRY2 genes associated with protection from GDM regardless of criteria applied (p < 0.025). 30089489 2018
Diabetes Mellitus, Non-Insulin-Dependent
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
0.020 GeneticVariation BEFREE We analyzed nine single-nucleotide polymorphisms (SNPs), including rs340874 (PROX1), rs4607517 (GCK), rs2191349 (DGKB-TMEM195), rs7034200 (GLIS3), rs10885122 (ADRA2A), rs174550 (FADS1), rs11605924 (CRY2), rs10830963 (MTNR1B) and rs35767 (IGF1). rs340874 (PROX1) and rs174550 (FADS1) were significantly associated with T2D (P=0.0078, OR: 1.12; and P=0.0071, OR: 1.12, respectively). 22992776 2012
Diabetes Mellitus, Non-Insulin-Dependent
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
0.020 GeneticVariation BEFREE In addition, we also found modest evidence for the association of CRY2-rs11605924 with combined IFG/type 2 diabetes. 21747906 2011