rs11749255, None

N. diseases: 1
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Resistant hypertensive disorder
CUI: C0745130
Disease: Resistant hypertensive disorder
0.010 GeneticVariation BEFREE A genetic risk score for RHTN was created by summing the risk alleles of replicated RHTN signals. rs11749255 in MSX2 was associated with RHTN in INVEST (odds ratio (OR) (95% CI) = 1.50 (1.2-1.8), p = 7.3 × 10<sup>-5</sup>) and replicated in SPS3 (OR = 2.0 (1.4-2.8), p = 4.3 × 10<sup>-5</sup>), with genome-wide significance in meta-analysis (OR = 1.60 (1.3-1.9), p = 3.8 × 10<sup>-8</sup>). 30237584 2019