rs121913236, KRAS

N. diseases: 4
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Colorectal Neoplasms
CUI: C0009404
Disease: Colorectal Neoplasms
0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Congenital Hyperinsulinism
CUI: C3888018
Disease: Congenital Hyperinsulinism
0.010 GeneticVariation BEFREE A previously reported individual with the rare HRAS p.Gln22Lys had hyperinsulinemic hypoglycemia. 26572961 2016
Hyperinsulinemic hypoglycemia
CUI: C1864903
Disease: Hyperinsulinemic hypoglycemia
0.010 GeneticVariation BEFREE A previously reported individual with the rare HRAS p.Gln22Lys had hyperinsulinemic hypoglycemia. 26572961 2016
Metastatic non-small cell lung cancer
CUI: C0278987
Disease: Metastatic non-small cell lung cancer
0.010 GeneticVariation BEFREE Herein we identified a KRAS Q22K mutation and frameshift mutations in the genes encoding serine/threonine kinase 11 (STK11) and ataxia telangiectasia mutated serine/threonine kinase (ATM) by next-generation sequencing in a patient with ALK rearrangement-positive oligo-metastatic NSCLC, whose disease progressed while on two ALK-targeted therapies. 25964588 2015