rs1284398161, MAP2K1

N. diseases: 1
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Motor neuron atrophy
CUI: C4024896
Disease: Motor neuron atrophy
0.010 GeneticVariation BEFREE The severe neurodegeneration and neuroinflammation that occur in mnd2 (motor neuron degeneration 2) mice result from loss of the protease activity of Omi by the point mutation S276C; however, the substrates of Omi that induce neurodegeneration are unknown. 22912494 2012