Myocardial Infarction
|
|
0.040 |
GeneticVariation
|
BEFREE |
No significant association was detected between rs668 and rs12953 with MI under any of the inheritance models.
|
23906939 |
2013 |
Myocardial Infarction
|
|
0.040 |
GeneticVariation
|
BEFREE |
The frequency of the Gly670Arg polymorphism was significantly higher in patients with myocardial infarction (MI), whereas the frequencies of the other two SNP (Leu125Val and Ser563Asn) were not significantly different between patients and controls.
|
17460171 |
2007 |
Myocardial Infarction
|
|
0.040 |
GeneticVariation
|
BEFREE |
The PECAM1 Leu125Val and Ser563Asn polymorphisms may increase the risk of atherosclerosis but not necessarily of MI.
|
14575520 |
2003 |
Myocardial Infarction
|
|
0.040 |
GeneticVariation
|
BEFREE |
Polymorphisms in the platelet-endothelial cell adhesion molecule-1 (PECAM-1) gene, Asn563Ser and Gly670Arg, associated with myocardial infarction in the Japanese.
|
11795274 |
2001 |
Coronary Artery Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Of the 137 angiographically confirmed patients (> or =70% stenosis) of CAD and 110 controls in Asian Indian population, two single nucleotide polymorphisms (SNPs) of PECAM-1 gene, C+373G (Leu125Val) at exon 3 and G+1688A (Ser563Asn) at exon 8 were analyzed by polymerase chain reaction-restriction fragment-length polymorphism (PCR-RFLP) strategy.
|
15756041 |
2005 |
Coronary Artery Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
We analyzed two single nucleotide polymorphisms (SNPs) of PECAM-1 gene C+373G (Leu125Val) at exon 3, which encodes the first extracellular (Ig)-like domain that mediates the homophilic binding of PECAM-1, and G+1688A (Ser563Asn) at exon 8 in 144 angiographically documented (> or =70% stenosis) patients with CAD and 150 age- and sex-matched controls in the Chinese population in Singapore, using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) strategy.
|
15589815 |
2004 |
Deep Vein Thrombosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The present study analyzed the single nucleotide polymorphisms (SNPs) of PECAM-1, namely Leu125Val (C373G), Asn563Ser (T1688C) and Gly670Arg (C2008T), in Chinese patients with DVT and age-and gender-matched controls, using polymerase chain reaction-restriction fragment length polymorphism analysis.
|
25846278 |
2015 |
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
Atherosclerotic complications were more frequent in SLE patients with AG genotype (rs12953) than those with AA genotype (p = 0.021).
|
25201689 |
2014 |
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The frequencies of 373C (rs668) and 1688A (rs12953) alleles were higher in RA patients when compared to controls (p values, 0.028 and 0.016).
|
25201689 |
2014 |
Graft-vs-Host Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Acute graft-vs.-host disease correlates with the disparity for the PECAM-1 S536N polymorphism only in the HLA-B44-like positive Tunisian recipients of HSCs.
|
20850712 |
2010 |
Acute myocardial infarction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The frequency of the Gly670Arg polymorphism was significantly higher in patients with AMI (58.9% vs. 48.3%; P = 0.019), whereas the frequencies of the other two SNPs (Leu125Val and Ser563Asn) were not significantly different between patients and controls.
|
15265022 |
2004 |
Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The PECAM1 Leu125Val and Ser563Asn polymorphisms may increase the risk of atherosclerosis but not necessarily of MI.
|
14575520 |
2003 |
Atherosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The PECAM1 Leu125Val and Ser563Asn polymorphisms may increase the risk of atherosclerosis but not necessarily of MI.
|
14575520 |
2003 |