rs13042395, SLC52A3

N. diseases: 13
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Esophageal Neoplasms
CUI: C0014859
Disease: Esophageal Neoplasms
0.730 GeneticVariation BEFREE Significant associations were found between SLC52A3 rs13042395 polymorphism and decreased cancer risk among esophageal cancer, Asians, female, normal BMI and old age groups. 27600099 2016
Esophageal Neoplasms
CUI: C0014859
Disease: Esophageal Neoplasms
0.730 GeneticVariation BEFREE Two SNPs, rs753955 and rs13042395, were associated with the risk of non-cardia GC in different genetic models (p < 0.05).No SNPs were associated with EC. 26176862 2015
Esophageal Neoplasms
CUI: C0014859
Disease: Esophageal Neoplasms
0.730 GeneticVariation BEFREE However, there was no significant association between the C20orf54 rs13042395 genotype and esophageal cancer risk (adjusted OR = 0.99, 95 % CI = 0.63-1.57 for C20orf54 rs13042395 TT vs. CC). 22744421 2012
Esophageal Neoplasms
CUI: C0014859
Disease: Esophageal Neoplasms
0.730 GeneticVariation GWASDB Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. 20729853 2010
Squamous cell carcinoma of esophagus
0.040 GeneticVariation BEFREE C20orf54 rs13042395 was not associated with ESCC under any genetic model. 30666517 2019
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.040 GeneticVariation BEFREE SLC52A3 rs13042395 showed an interaction with alcohol drinking in risk of GC. 28220687 2017
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.040 GeneticVariation BEFREE SLC52A3 rs13042395 showed an interaction with alcohol drinking in risk of GC. 28220687 2017
Squamous cell carcinoma of esophagus
0.040 GeneticVariation BEFREE The rs13042395 polymorphism in SLC52A3 is associated with regional lymph node metastasis and relapse-free survival in ESCC patients. 27472962 2016
Squamous cell carcinoma of esophagus
0.040 GeneticVariation BEFREE In conclusion, C20orf54 rs13042395 polymorphism was significantly associated with decreased ESCC and GCA risk especially for the subjects with under-weight or normal. 26154995 2015
Squamous cell carcinoma of esophagus
0.040 GeneticVariation BEFREE We observed that the rs2274223 polymorphism was associated with an increased risk of ESCC in this Korean case-control study and that age may modify the association between the rs13042395 polymorphism and the risk of ESCC. 24152165 2015
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.040 GeneticVariation BEFREE These results indicated that rs17728461 may be specifically associated with the risk of NSCLC. rs753955 and rs13042395 were specifically associated with susceptibility to non-cardia GC in Ningxia Han Chinese. 26176862 2015
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.040 GeneticVariation BEFREE These results indicated that rs17728461 may be specifically associated with the risk of NSCLC. rs753955 and rs13042395 were specifically associated with susceptibility to non-cardia GC in Ningxia Han Chinese. 26176862 2015
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.040 GeneticVariation BEFREE However, no significant association was detected between rs13042395 at 20p13 and GC risk (OR = 1.04, 95% CI: 0.94-1.15; P = 0.452). 21427165 2011
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.040 GeneticVariation BEFREE Imputation analyses also confirmed previously reported associations of rs2294008 and rs2976392 on 8q24, rs4072037 on 1q22 and rs13042395 on 20p13 with non-cardia gastric cancer susceptibility in the Han Chinese population. 22037551 2011
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.040 GeneticVariation BEFREE However, no significant association was detected between rs13042395 at 20p13 and GC risk (OR = 1.04, 95% CI: 0.94-1.15; P = 0.452). 21427165 2011
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.040 GeneticVariation BEFREE Imputation analyses also confirmed previously reported associations of rs2294008 and rs2976392 on 8q24, rs4072037 on 1q22 and rs13042395 on 20p13 with non-cardia gastric cancer susceptibility in the Han Chinese population. 22037551 2011
Esophageal carcinoma
CUI: C0152018
Disease: Esophageal carcinoma
0.030 GeneticVariation BEFREE Significant associations were found between SLC52A3 rs13042395 polymorphism and decreased cancer risk among esophageal cancer, Asians, female, normal BMI and old age groups. 27600099 2016
Malignant Neoplasms
CUI: C0006826
Disease: Malignant Neoplasms
0.030 GeneticVariation BEFREE SLC52A3 rs13042395 C>T polymorphism might be a potential biomarker for cancer susceptibility. 27600099 2016
Malignant neoplasm of esophagus
CUI: C0546837
Disease: Malignant neoplasm of esophagus
0.030 GeneticVariation BEFREE Significant associations were found between SLC52A3 rs13042395 polymorphism and decreased cancer risk among esophageal cancer, Asians, female, normal BMI and old age groups. 27600099 2016
Primary malignant neoplasm
CUI: C1306459
Disease: Primary malignant neoplasm
0.030 GeneticVariation BEFREE SLC52A3 rs13042395 C>T polymorphism might be a potential biomarker for cancer susceptibility. 27600099 2016
Esophageal carcinoma
CUI: C0152018
Disease: Esophageal carcinoma
0.030 GeneticVariation BEFREE Two SNPs, rs753955 and rs13042395, were associated with the risk of non-cardia GC in different genetic models (p < 0.05).No SNPs were associated with EC. 26176862 2015
Primary malignant neoplasm
CUI: C1306459
Disease: Primary malignant neoplasm
0.030 GeneticVariation BEFREE Subgroup analysis was also stratified by body mass index (BMI), rs13042395 polymorphism was significantly associated with a subtly decreased cancer risk in under-weight group and normal group, but no association was observed in over-weight group. 26154995 2015
Malignant Neoplasms
CUI: C0006826
Disease: Malignant Neoplasms
0.030 GeneticVariation BEFREE Subgroup analysis was also stratified by body mass index (BMI), rs13042395 polymorphism was significantly associated with a subtly decreased cancer risk in under-weight group and normal group, but no association was observed in over-weight group. 26154995 2015
Malignant neoplasm of esophagus
CUI: C0546837
Disease: Malignant neoplasm of esophagus
0.030 GeneticVariation BEFREE Two SNPs, rs753955 and rs13042395, were associated with the risk of non-cardia GC in different genetic models (p < 0.05).No SNPs were associated with EC. 26176862 2015
Primary malignant neoplasm
CUI: C1306459
Disease: Primary malignant neoplasm
0.030 GeneticVariation BEFREE We observed no association between rs13042395 in Corf54 and the risk of gastric or oesphageal cancer in either of the two studies. 22805490 2012