rs1367215622, PHLPP2

N. diseases: 2
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Transitional cell carcinoma of bladder
CUI: C0279680
Disease: Transitional cell carcinoma of bladder
0.010 GeneticVariation BEFREE Stable <i>TMCO1</i> (wild-type) overexpression suppressed, whereas T33A and S60A mutants recovered, tumor size in xenograft mice.<b>Conclusions:</b> Clinical associations, xenograft mice, and <i>in vitro</i> indications provide solid evidence that the <i>TMCO1</i> gene is a novel tumor suppressor in UBUCs. 28972042 2017
Neoplasms
CUI: C0027651
Disease: Neoplasms
0.010 GeneticVariation BEFREE Stable <i>TMCO1</i> (wild-type) overexpression suppressed, whereas T33A and S60A mutants recovered, tumor size in xenograft mice.<b>Conclusions:</b> Clinical associations, xenograft mice, and <i>in vitro</i> indications provide solid evidence that the <i>TMCO1</i> gene is a novel tumor suppressor in UBUCs. 28972042 2017