rs1390938, SLC18A1

N. diseases: 7
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Major Depressive Disorder
CUI: C1269683
Disease: Major Depressive Disorder
0.010 GeneticVariation BEFREE The possible interaction effect between rs1390938 and MDD on white matter integrity was also assessed. 28408293 2017
Autism Spectrum Disorders
CUI: C1510586
Disease: Autism Spectrum Disorders
0.010 GeneticVariation BEFREE Haplotype analysis revealed that C A T T and C A T G haplotypes (rs2270637, rs1390938, rs2279709 and rs2270641 respectively) have a protective effect against ASD. 28476685 2017
Alcohol withdrawal syndrome
CUI: C0236663
Disease: Alcohol withdrawal syndrome
0.010 GeneticVariation BEFREE This study shows that genetic variants in VMAT1, including the functional SNP rs1390938, contribute to the severity of AW in patients of European descent. 26876819 2016
Anxiety
CUI: C0003467
Disease: Anxiety
0.010 GeneticVariation BEFREE A common single nucleotide polymorphism in the vesicular monoamine transporter 1 gene (VMAT1 rs1390938 G/A; Thr136Ile) has been reported as functional in vitro and associated with bipolar disorder and anxiety. 26861143 2016
Anxiety Disorders
CUI: C0003469
Disease: Anxiety Disorders
0.010 GeneticVariation BEFREE A common single nucleotide polymorphism in the vesicular monoamine transporter 1 gene (VMAT1 rs1390938 G/A; Thr136Ile) has been reported as functional in vitro and associated with bipolar disorder and anxiety. 26861143 2016
Bronchopulmonary Dysplasia
CUI: C0006287
Disease: Bronchopulmonary Dysplasia
0.010 GeneticVariation BEFREE Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020). 16936705 2006
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.010 GeneticVariation BEFREE Genotypes of 585 patients with BPD type I and 563 control subjects were obtained for three missense single nucleotide polymorphisms (SNPs) (Thr4Pro, Thr98Ser, Thr136Ile) and four non-coding SNPs (rs988713, rs2279709, rs3735835, rs1497020). 16936705 2006