|
Hepatocarcinogenesis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Taken together, our findings provided evidence that rs145204276 may contribute to hepatocarcinogenesis by affecting methylation status of the GAS5 promoter and subsequently its transcriptional activity thus serving as a potential therapy target for HCC.
|
26163879 |
2015 |
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Taken together, our findings provided strong evidence for the hypothesis that GAS5 rs145204276 were significantly associated with the susceptibility and progression of CRC.
|
27863421 |
2016 |
|
Neoplasm Metastasis
|
|
0.030 |
GeneticVariation
|
BEFREE |
In current two-stage, case-control study, we systematically evaluated the potential role of lncRNA GAS5 and its genetic variation rs145204276 in the development and metastasis process of CRC in a Chinese population.
|
27863421 |
2016 |
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
In current study, we investigated the possible association between susceptibility of lung cancer and GAS5 rs145204276, which showed contradictory roles in carcinogenesis of colorectal cancer and hepatocellular carcinoma.
|
29207621 |
2017 |
|
Malignant neoplasm of colon and/or rectum
|
|
0.020 |
GeneticVariation
|
BEFREE |
In current study, we investigated the possible association between susceptibility of lung cancer and GAS5 rs145204276, which showed contradictory roles in carcinogenesis of colorectal cancer and hepatocellular carcinoma.
|
29207621 |
2017 |
|
Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
Taken together, our findings provided strong evidence for the hypothesis that GAS5 rs145204276 were significantly associated with the susceptibility of lung cancer, and GAS5 functions as a tumor suppressor in carcinogenesis of lung cancer.
|
29207621 |
2017 |
|
Liver carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
In current study, we investigated the possible association between susceptibility of lung cancer and GAS5 rs145204276, which showed contradictory roles in carcinogenesis of colorectal cancer and hepatocellular carcinoma.
|
29207621 |
2017 |
|
Malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
Taken together, our findings provided strong evidence for the hypothesis that GAS5 rs145204276 were significantly associated with the susceptibility of lung cancer, and GAS5 functions as a tumor suppressor in carcinogenesis of lung cancer.
|
29207621 |
2017 |
|
Carcinogenesis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Taken together, our findings provided strong evidence for the hypothesis that GAS5 rs145204276 were significantly associated with the susceptibility of lung cancer, and GAS5 functions as a tumor suppressor in carcinogenesis of lung cancer.
|
29207621 |
2017 |
|
Primary malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
Taken together, our findings provided strong evidence for the hypothesis that GAS5 rs145204276 were significantly associated with the susceptibility of lung cancer, and GAS5 functions as a tumor suppressor in carcinogenesis of lung cancer.
|
29207621 |
2017 |
|
Carcinoma of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
Taken together, our findings provided strong evidence for the hypothesis that GAS5 rs145204276 were significantly associated with the susceptibility of lung cancer, and GAS5 functions as a tumor suppressor in carcinogenesis of lung cancer.
|
29207621 |
2017 |
|
Neoplasm Metastasis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The allele del of rs145204276 is associated with a remarkably lower incidence of cancer progression and metastasis.
|
29557411 |
2018 |
|
Neoplasm Metastasis
|
|
0.030 |
GeneticVariation
|
BEFREE |
We confirmed that rs145204276 of GAS5 is a functional variant associated with the susceptibility and metastasis of GC.
|
29602737 |
2018 |
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Previous studies showed that genetic variant rs145204276 in the promoter region of GAS5 was associated with the development of human cancer including colorectal cancer and hepatocellular cancer.
|
30013899 |
2018 |
|
Stomach Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
The variant rs145204276 of GAS5 is associated with the development and prognosis of GC.
|
29557411 |
2018 |
|
Malignant neoplasm of stomach
|
|
0.020 |
GeneticVariation
|
BEFREE |
The variant rs145204276 of GAS5 is associated with the development and prognosis of GC.
|
29557411 |
2018 |
|
Stomach Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
We confirmed that rs145204276 of GAS5 is a functional variant associated with the susceptibility and metastasis of GC.
|
29602737 |
2018 |
|
Malignant neoplasm of stomach
|
|
0.020 |
GeneticVariation
|
BEFREE |
We confirmed that rs145204276 of GAS5 is a functional variant associated with the susceptibility and metastasis of GC.
|
29602737 |
2018 |
|
Liver carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Previous studies showed that genetic variant rs145204276 in the promoter region of GAS5 was associated with the development of human cancer including colorectal cancer and hepatocellular cancer.
|
30013899 |
2018 |
|
Malignant neoplasm of colon and/or rectum
|
|
0.020 |
GeneticVariation
|
BEFREE |
Previous studies showed that genetic variant rs145204276 in the promoter region of GAS5 was associated with the development of human cancer including colorectal cancer and hepatocellular cancer.
|
30013899 |
2018 |
|
Atherosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In summary, rs145204276 was associated with the risk of atherosclerosis by affecting the proliferation and apoptosis of endothelial cells via regulating the GAS5/miR-21/PDCD4 signaling pathway.
|
30205366 |
2018 |
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
Previous studies showed that genetic variant rs145204276 in the promoter region of GAS5 was associated with the development of human cancer including colorectal cancer and hepatocellular cancer.
|
30013899 |
2018 |
|
Tumor Progression
|
|
0.010 |
GeneticVariation
|
BEFREE |
The allele del of rs145204276 is associated with a remarkably lower incidence of cancer progression and metastasis.
|
29557411 |
2018 |
|
Adult Hepatocellular Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Previous studies showed that genetic variant rs145204276 in the promoter region of GAS5 was associated with the development of human cancer including colorectal cancer and hepatocellular cancer.
|
30013899 |
2018 |
|
Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In summary, rs145204276 was associated with the risk of atherosclerosis by affecting the proliferation and apoptosis of endothelial cells via regulating the GAS5/miR-21/PDCD4 signaling pathway.
|
30205366 |
2018 |