Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Neoplasm Metastasis
CUI: C0027627
Disease: Neoplasm Metastasis
0.030 GeneticVariation BEFREE The allele del of rs145204276 is associated with a remarkably lower incidence of cancer progression and metastasis. 29557411 2018
Neoplasm Metastasis
CUI: C0027627
Disease: Neoplasm Metastasis
0.030 GeneticVariation BEFREE We confirmed that rs145204276 of GAS5 is a functional variant associated with the susceptibility and metastasis of GC. 29602737 2018
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.030 GeneticVariation BEFREE Previous studies showed that genetic variant rs145204276 in the promoter region of GAS5 was associated with the development of human cancer including colorectal cancer and hepatocellular cancer. 30013899 2018
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.030 GeneticVariation BEFREE In current study, we investigated the possible association between susceptibility of lung cancer and GAS5 rs145204276, which showed contradictory roles in carcinogenesis of colorectal cancer and hepatocellular carcinoma. 29207621 2017
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.030 GeneticVariation BEFREE Taken together, our findings provided strong evidence for the hypothesis that GAS5 rs145204276 were significantly associated with the susceptibility and progression of CRC. 27863421 2016
Neoplasm Metastasis
CUI: C0027627
Disease: Neoplasm Metastasis
0.030 GeneticVariation BEFREE In current two-stage, case-control study, we systematically evaluated the potential role of lncRNA GAS5 and its genetic variation rs145204276 in the development and metastasis process of CRC in a Chinese population. 27863421 2016
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.020 GeneticVariation BEFREE Patients with PC were recruited and grouped according to their specific genotypes of rs55829688 and rs145204276. 30317620 2019
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.020 GeneticVariation BEFREE We aimed to investigate the effect of variant rs145204276 of GAS5 on the prostate cancer susceptibility and clinicopathologic characteristics. 31673232 2019
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.020 GeneticVariation BEFREE Patients with PC were recruited and grouped according to their specific genotypes of rs55829688 and rs145204276. 30317620 2019
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.020 GeneticVariation BEFREE We aimed to investigate the effect of variant rs145204276 of GAS5 on the prostate cancer susceptibility and clinicopathologic characteristics. 31673232 2019
Neoplasms
CUI: C0027651
Disease: Neoplasms
0.020 GeneticVariation BEFREE The frequency of the allele del of rs145204276 were compared between the patients and the controls to evaluate the impact of tumor susceptibility and the correlation of clinicopathological variables. 31673232 2019
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.020 GeneticVariation BEFREE The variant rs145204276 of GAS5 is associated with the development and prognosis of GC. 29557411 2018
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.020 GeneticVariation BEFREE The variant rs145204276 of GAS5 is associated with the development and prognosis of GC. 29557411 2018
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.020 GeneticVariation BEFREE We confirmed that rs145204276 of GAS5 is a functional variant associated with the susceptibility and metastasis of GC. 29602737 2018
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.020 GeneticVariation BEFREE We confirmed that rs145204276 of GAS5 is a functional variant associated with the susceptibility and metastasis of GC. 29602737 2018
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.020 GeneticVariation BEFREE Previous studies showed that genetic variant rs145204276 in the promoter region of GAS5 was associated with the development of human cancer including colorectal cancer and hepatocellular cancer. 30013899 2018
Malignant neoplasm of colon and/or rectum
0.020 GeneticVariation BEFREE Previous studies showed that genetic variant rs145204276 in the promoter region of GAS5 was associated with the development of human cancer including colorectal cancer and hepatocellular cancer. 30013899 2018
Malignant neoplasm of colon and/or rectum
0.020 GeneticVariation BEFREE In current study, we investigated the possible association between susceptibility of lung cancer and GAS5 rs145204276, which showed contradictory roles in carcinogenesis of colorectal cancer and hepatocellular carcinoma. 29207621 2017
Neoplasms
CUI: C0027651
Disease: Neoplasms
0.020 GeneticVariation BEFREE Taken together, our findings provided strong evidence for the hypothesis that GAS5 rs145204276 were significantly associated with the susceptibility of lung cancer, and GAS5 functions as a tumor suppressor in carcinogenesis of lung cancer. 29207621 2017
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.020 GeneticVariation BEFREE In current study, we investigated the possible association between susceptibility of lung cancer and GAS5 rs145204276, which showed contradictory roles in carcinogenesis of colorectal cancer and hepatocellular carcinoma. 29207621 2017
Secondary malignant neoplasm of lymph node
0.010 GeneticVariation BEFREE In conclusion, the rs145204276 polymorphic genotype of GAS5 can predict the risk of lymph </span>node metastasis. 31673232 2019
Tumor Cell Invasion
CUI: C1269955
Disease: Tumor Cell Invasion
0.010 GeneticVariation BEFREE The results shown that patients who carries genotype ins/del or del/del at SNP rs145204276 showed decreased risk of pathological lymph node metastasis disease (OR=0.545, p=0.043) and risk of seminal vesicle invasion (OR=0.632, p=0.022) comparing to with genotype ins/ins. 31673232 2019
Breast Carcinoma
CUI: C0678222
Disease: Breast Carcinoma
0.010 GeneticVariation BEFREE The rs145204276 del allele might protect against the development of BC via inducing the promoter activity by binding to transcriptional factor specificity protein 1, and finally resulting in higher levels of GAS5. 30846409 2019
Febrile Convulsions
CUI: C0009952
Disease: Febrile Convulsions
0.010 GeneticVariation BEFREE Association between indel polymorphism (rs145204276) in the promoter region of lncRNA GAS5 and the risk of febrile convulsion. 30656683 2019
Malignant neoplasm of breast
CUI: C0006142
Disease: Malignant neoplasm of breast
0.010 GeneticVariation BEFREE The rs145204276 del allele might protect against the development of BC via inducing the promoter activity by binding to transcriptional factor specificity protein 1, and finally resulting in higher levels of GAS5. 30846409 2019