rs1545843, LOC107984536

N. diseases: 6
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Major Depressive Disorder
CUI: C1269683
Disease: Major Depressive Disorder
0.720 GeneticVariation BEFREE We observed an association between the SLC6A15 rs1545843 and resting-state brain function of the corpus callosum, cingulum and the frontal, parietal, and temporal lobes in MDD patients, which may be involved in the pathogenesis of MDD. 28915082 2017
Major Depressive Disorder
CUI: C1269683
Disease: Major Depressive Disorder
0.720 GeneticVariation BEFREE We observed an association between the risk allele of the SLC6A15 gene rs1545843 and the WM integrity of the PHC in MDD patients, which is known to play an important role in the neural circuit involved in emotion processing. 27723767 2016
Major Depressive Disorder
CUI: C1269683
Disease: Major Depressive Disorder
0.720 GeneticVariation GWASDB The neuronal transporter gene SLC6A15 confers risk to major depression. 21521612 2011
Depressed mood
CUI: C0344315
Disease: Depressed mood
0.020 GeneticVariation BEFREE Among patients with PD, depression is associated with polymorphism at rs78162420 and rs1545843, both previously linked with depression. 28320136 2017
Mental Depression
CUI: C0011570
Disease: Mental Depression
0.020 GeneticVariation BEFREE Among patients with PD, depression is associated with polymorphism at rs78162420 and rs1545843, both previously linked with depression. 28320136 2017
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.020 GeneticVariation BEFREE Among patients with PD, depression is associated with polymorphism at rs78162420 and rs1545843, both previously linked with depression. 28320136 2017
Depressed mood
CUI: C0344315
Disease: Depressed mood
0.020 GeneticVariation BEFREE Recently, a variant (rs1545843) affecting transcription of the human SLC6A15 gene has been associated with depression in a genome-wide association study. 22475622 2013
Mental Depression
CUI: C0011570
Disease: Mental Depression
0.020 GeneticVariation BEFREE Recently, a variant (rs1545843) affecting transcription of the human SLC6A15 gene has been associated with depression in a genome-wide association study. 22475622 2013
Depressive disorder
CUI: C0011581
Disease: Depressive disorder
0.020 GeneticVariation BEFREE Recently, a variant (rs1545843) affecting transcription of the human SLC6A15 gene has been associated with depression in a genome-wide association study. 22475622 2013
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.010 GeneticVariation BEFREE Among patients with PD, depression is associated with polymorphism at rs78162420 and rs1545843, both previously linked with depression. 28320136 2017
Unipolar Depression
CUI: C0041696
Disease: Unipolar Depression
0.010 GeneticVariation BEFREE Against the background of stress impacting on the activity of the HPA axis, we have investigated alterations of adrenocorticotropic hormone (ACTH) and cortisol secretion in the combined dexamethasone/corticotrophin-releasing hormone (Dex/CRH) test as well as memory and attention performance in a sample of 248 patients with unipolar depression and 172 healthy control subjects genotyped for rs1545843. 22475622 2013