|
response to bronchodilator
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
|
26634245 |
2015 |
|
Forced expiratory volume function
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
|
26634245 |
2015 |
|
Chronic Obstructive Airway Disease
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
|
26634245 |
2015 |
|
Smoking Behaviors
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analyses of smoking behaviors in African Americans.
|
22832964 |
2012 |
|
Smoking
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide meta-analyses of smoking behaviors in African Americans.
|
22832964 |
2012 |
|
Forced expiratory volume function
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
|
21946350 |
2011 |
|
Pulmonary function (finding)
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
|
21946350 |
2011 |
|
Respiratory Function Tests
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
|
21946350 |
2011 |
|
Pulmonary function
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
|
21946350 |
2011 |
|
Smoking Behaviors
|
|
0.700 |
GeneticVariation
|
GWASDB |
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
|
20418888 |
2010 |
|
Smoking Behaviors
|
|
0.700 |
GeneticVariation
|
GWASDB |
Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
|
20418889 |
2010 |
|
Malignant neoplasm of lung
|
|
0.020 |
GeneticVariation
|
BEFREE |
In the combined analysis, we confirmed two loci to be associated with lung cancer that achieved the threshold of genome-wide significance: 15q25.1 marked by rs2036527 (p=1.3×10(-9); OR=1.32; 95% CI=1.20-1.44) near CHRNA5, and 5p15.33 marked by rs2853677 (p=2.8×10(-9); OR=1.28; 95% CI=1.18-1.39) near TERT.
|
27393504 |
2016 |
|
Carcinoma of lung
|
|
0.020 |
GeneticVariation
|
BEFREE |
In the combined analysis, we confirmed two loci to be associated with lung cancer that achieved the threshold of genome-wide significance: 15q25.1 marked by rs2036527 (p=1.3×10(-9); OR=1.32; 95% CI=1.20-1.44) near CHRNA5, and 5p15.33 marked by rs2853677 (p=2.8×10(-9); OR=1.28; 95% CI=1.18-1.39) near TERT.
|
27393504 |
2016 |
|
Primary malignant neoplasm of lung
|
|
0.020 |
GeneticVariation
|
BEFREE |
In the combined analysis, we confirmed two loci to be associated with lung cancer that achieved the threshold of genome-wide significance: 15q25.1 marked by rs2036527 (p=1.3×10(-9); OR=1.32; 95% CI=1.20-1.44) near CHRNA5, and 5p15.33 marked by rs2853677 (p=2.8×10(-9); OR=1.28; 95% CI=1.18-1.39) near TERT.
|
27393504 |
2016 |
|
Malignant neoplasm of lung
|
|
0.020 |
GeneticVariation
|
BEFREE |
Associations of SNPs in LOC123688 (rs10519203; odds ratio [OR] = 1.60, 95% confidence interval [CI] = 1.25 to 2.05, P = .00016), CHRNA5 (rs2036527; OR = 1.67, 95% CI = 1.26 to 2.21, P = .00031), and CHRNA3 (rs1051730; OR = 1.81, 95% CI = 1.26 to 2.59, P = .00137) genes with lung cancer risk reached Bonferroni-corrected levels of statistical significance (all statistical tests were two-sided).
|
20554942 |
2010 |
|
Carcinoma of lung
|
|
0.020 |
GeneticVariation
|
BEFREE |
Associations of SNPs in LOC123688 (rs10519203; odds ratio [OR] = 1.60, 95% confidence interval [CI] = 1.25 to 2.05, P = .00016), CHRNA5 (rs2036527; OR = 1.67, 95% CI = 1.26 to 2.21, P = .00031), and CHRNA3 (rs1051730; OR = 1.81, 95% CI = 1.26 to 2.59, P = .00137) genes with lung cancer risk reached Bonferroni-corrected levels of statistical significance (all statistical tests were two-sided).
|
20554942 |
2010 |
|
Primary malignant neoplasm of lung
|
|
0.020 |
GeneticVariation
|
BEFREE |
Associations of SNPs in LOC123688 (rs10519203; odds ratio [OR] = 1.60, 95% confidence interval [CI] = 1.25 to 2.05, P = .00016), CHRNA5 (rs2036527; OR = 1.67, 95% CI = 1.26 to 2.21, P = .00031), and CHRNA3 (rs1051730; OR = 1.81, 95% CI = 1.26 to 2.59, P = .00137) genes with lung cancer risk reached Bonferroni-corrected levels of statistical significance (all statistical tests were two-sided).
|
20554942 |
2010 |
|
Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Single-nucleotide polymorphisms rs421629 on 5p15.33 and rs1948, rs660652, rs8040868 and rs2036527 on 15q25.1, previously identified as lung cancer risk or nicotine-addiction modifiers, were associated with tumor DNA methylation levels in the promoters of TERT and CHRNB4 (P<0.001), respectively, in two independent sample sets (n=82; n=150).
|
22945651 |
2013 |