|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
The present study suggested that TNFSF4 rs1234315 and rs2205960 polymorphisms were associated with SLE susceptibility.
|
31299880 |
2019 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
GWASCAT |
Transancestral mapping and genetic load in systemic lupus erythematosus.
|
28714469 |
2017 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
The frequency of minor T allele of TNFSF4 rs2205960 was significant in Chinese and Indian patients with SLE, with P values of 0.05 (OR = 1.27, 95% CI: 1.00-1.61) and 0.004 (OR = 3.16, 95% CI: 1.41-7.05), respectively.
|
27519474 |
2016 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
GWASCAT |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
The SNPs of TNFSF4 were associated with renal involvement in lupus patients from the Chinese population (P values for rs2205960 and rs10489265 were 0.014 and 0.005 in additive model, resp.).
|
23936824 |
2013 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
The results of our meta-analysis suggest that the TNFSF4 rs2205960 polymorphism may confer susceptibility to SLE in different populations and that the TNFSF4 rs1234315 polymorphism is associated with susceptibility to SLE in Asians.
|
22850862 |
2013 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
GWASDB |
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.
|
23273568 |
2013 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
Single-marker analysis validated the association of BLK rs2736340 (P=4.25×10(-6)) as well as TNFSF4 rs2205960 (P=2.82×10(-5)) and TNFAIP3 rs5029939 (P=1.92×10(-3)) with SLE susceptibility in Chinese.
|
21905002 |
2012 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
Known SLE and SSc TNFSF4 susceptibility variants (rs2205960, rs1234317, rs12039904, rs10912580, and rs844648) were genotyped in 1031 patients with SSc and 1014 controls of French white ancestry.
|
22422496 |
2012 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
A total of 21 comparative studies were included in this meta-analysis; meta-analysis showed an association between the minor allele of rs2205960 of TNFSF4 and SLE in all study subjects (odds ratio [OR]=1.356, 95% confidence interval [CI]=1.275-1.442, p<1.0×10(-9)).
|
22820624 |
2012 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
BEFREE |
In TNFSF4, rs2205960 was associated with SLE independently from the effect of rs844648 (P=6.26 x 10(-3)), but not vice versa (P=0.55).
|
19357697 |
2009 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
GWASCAT |
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.
|
19838195 |
2009 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
GWASDB |
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.
|
19838193 |
2009 |
|
Lupus Erythematosus, Systemic
|
|
0.880 |
GeneticVariation
|
GWASCAT |
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.
|
19838193 |
2009 |
|
Multiple Sclerosis
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
|
22190364 |
2011 |
|
Systemic Scleroderma
|
|
0.020 |
GeneticVariation
|
BEFREE |
We confirm TNFSF4 as an SSc susceptibility gene and rs2205960 as a putative causal variant with preferential association in the ACA+ SSc subphenotype.
|
22422496 |
2012 |
|
Systemic Scleroderma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Case-control comparisons revealed a significant association between susceptibility to SS</span>c and the minor alleles at SNPs rs1234314 (OR 1.20, 95% CI 1.04 to 1.4, p(FDR)=0.019), rs2205960 (OR 1.24, 95% CI 1.10 to 1.50, p(FDR)=0.019) and rs844648 (OR 1.16, 95% CI 1.01 to 1.30, p(FDR)=0.032).
|
19778912 |
2010 |
|
Primary Sjögren's syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
In TNFSF4, T allele and TT genotype of rs2205960, and G allele of rs1234313, were associated with pSS (p<0.05); T allele of rs2205960 was correlated with PBC (p<0.05) as a risk factor.
|
23622253 |
2013 |
|
Lupus Vulgaris
|
|
0.010 |
GeneticVariation
|
BEFREE |
The SNPs of TNFSF4 were associated with renal involvement in lupus patients from the Chinese population (P values for rs2205960 and rs10489265 were 0.014 and 0.005 in additive model, resp.).
|
23936824 |
2013 |
|
Lupus Erythematosus
|
|
0.010 |
GeneticVariation
|
BEFREE |
The SNPs of TNFSF4 were associated with renal involvement in lupus patients from the Chinese population (P values for rs2205960 and rs10489265 were 0.014 and 0.005 in additive model, resp.).
|
23936824 |
2013 |
|
Lymphopenia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our research suggests association of rs2205960-T with SLE across multiple groups and an independent non-risk signal at rs1234314-C. rs2205960-T is associated with autoantibody production and lymphopenia.
|
23874208 |
2013 |
|
Primary biliary cirrhosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In TNFSF4, T allele and TT genotype of rs2205960, and G allele of rs1234313, were associated with pSS (p<0.05); T allele of rs2205960 was correlated with PBC (p<0.05) as a risk factor.
|
23622253 |
2013 |
|
Lupus Erythematosus, Discoid
|
|
0.010 |
GeneticVariation
|
BEFREE |
The SNPs of TNFSF4 were associated with renal involvement in lupus patients from the Chinese population (P values for rs2205960 and rs10489265 were 0.014 and 0.005 in additive model, resp.).
|
23936824 |
2013 |