Coronary heart disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
BEFREE |
Five single-nucleotide polymorphisms, rs4977574 (CDKN2A/2B), rs12526453 (PHACTR1), rs646776 (CELSR2-PSRC1-SORT1), rs2259816 (HNF1A), and rs11206510 (PCSK9) showed directionally consistent associations with CHD in the 3 studies, with combined odds ratios (ORs) ranging from 1.17 to 1.25 (p = 0.03 to 0.0002).
|
22152955 |
2011 |
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
BEFREE |
In the LURIC Study cohort the A-allele of rs2259816 is associated with decreased CRP but not with coronary artery disease.
|
21062467 |
2010 |
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
New susceptibility locus for coronary artery disease on chromosome 3q22.3.
|
19198612 |
2009 |
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
New susceptibility locus for coronary artery disease on chromosome 3q22.3.
|
19198612 |
2009 |
C-reactive protein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
C-reactive protein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
New variants including ARG1 polymorphisms associated with C-reactive protein levels identified by genome-wide association and pathway analysis.
|
24763700 |
2014 |
C-reactive protein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
|
23844046 |
2013 |
C-reactive protein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.
|
22939635 |
2012 |
C-reactive protein measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women.
|
22939635 |
2012 |
Pseudocholinesterase Measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.
|
21943158 |
2011 |
Acute Chest Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
The alleles of rs12190287 (MRAS), rs121902287 (TCF21) and rs2259816 (HNF1a) were associated with a higher risk of ACS.
|
27888760 |
2017 |
Hypertriglyceridemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Hypertriglyceridemia was linked to the rs2393791_T (1.14 (1.02-1.27); P = 0.018), rs7310409_G (1.12 (1.01-1.25); P = 0.031), rs1169310_G (1.15 (1.04-1.28); P = 0.010), and rs1169313_CT+TT (1.24 (1.06-1.45); P = 0.008) and high low density lipoprotein-cholesterol levels were associated with rs2259820_T (1.23 (1.07-1.41); P = 0.004), rs2464196_T (1.22 (1.06-1.39); P = 0.004), and rs2259816_T (1.18 (1.02-1.36); P = 0.023).
|
25057215 |
2014 |
Diabetic Nephropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Despite no significance in genetic analysis of diabetic subjects, SNP rs2259816 in the HNF1A gene tended to associate with diabetic nephropathy in type 1 diabetic patients.
|
22849862 |
2012 |
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the LURIC Study cohort the A-allele of rs2259816 is associated with decreased CRP but not with coronary artery disease.
|
21062467 |
2010 |
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the LURIC Study cohort the A-allele of rs2259816 is associated with decreased CRP but not with coronary artery disease.
|
21062467 |
2010 |