|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
|
26681312 |
2016 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Acute myeloid leukemia with TP53 germ line mutations.
|
27621308 |
2016 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Prevalence and functional consequence of TP53 mutations in pediatric adrenocortical carcinoma: a children's oncology group study.
|
25584008 |
2015 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Regulation of the p53 response and its relationship to cancer.
|
26205489 |
2015 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Regulation of the p53 response and its relationship to cancer.
|
26205489 |
2015 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Targeted Resequencing of 30 Genes Improves the Detection of Deleterious Mutations in South Indian Women with Breast and/or Ovarian Cancers.
|
26225655 |
2015 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Successful treatment of a patient with Li-Fraumeni syndrome and metastatic lung adenocarcinoma harboring synchronous EGFR L858R and ERBB2 extracellular domain S310F mutations with the pan-HER inhibitor afatinib.
|
24835218 |
2014 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Li-Fraumeni and Li-Fraumeni-like syndrome among children diagnosed with pediatric cancer in Southern Brazil.
|
24122735 |
2013 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Li-Fraumeni and Li-Fraumeni-like syndrome among children diagnosed with pediatric cancer in Southern Brazil.
|
24122735 |
2013 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Establishment and characterization of the first pediatric adrenocortical carcinoma xenograft model identifies topotecan as a potential chemotherapeutic agent.
|
23406775 |
2013 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis.
|
23538418 |
2013 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Early onset HER2-positive breast cancer is associated with germline TP53 mutations.
|
21761402 |
2012 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.
|
21343334 |
2011 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.
|
21343334 |
2011 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation.
|
20128691 |
2010 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation.
|
20128691 |
2010 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes.
|
20522432 |
2010 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
The TP53 mutation, R337H, is associated with Li-Fraumeni and Li-Fraumeni-like syndromes in Brazilian families.
|
16494995 |
2007 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database.
|
17311302 |
2007 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database.
|
17311302 |
2007 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Prevalence of early onset colorectal cancer in 397 patients with classic Li-Fraumeni syndrome.
|
16401470 |
2006 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Mutant p53 proteins bind DNA in a DNA structure-selective mode.
|
15722483 |
2005 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Identification of five new families strengthens the link between childhood choroid plexus carcinoma and germline TP53 mutations.
|
15925506 |
2005 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
Mutant p53 proteins bind DNA in a DNA structure-selective mode.
|
15722483 |
2005 |
|
Li-Fraumeni Syndrome
|
|
0.810 |
CausalMutation
|
CLINVAR |
The TP53 mutational spectrum and frequency of CHEK2*1100delC in Li-Fraumeni-like kindreds.
|
15951970 |
2005 |