rs35719940, TERT

N. diseases: 3
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Dyskeratosis Congenita
CUI: C0265965
Disease: Dyskeratosis Congenita
0.700 CausalMutation CLINVAR
LEUKEMIA, ACUTE MYELOID, SUSCEPTIBILITY TO
CUI: C3275959
Disease: LEUKEMIA, ACUTE MYELOID, SUSCEPTIBILITY TO
0.700 SusceptibilityMutation CLINVAR
Leukemia, Myelocytic, Acute
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
0.020 GeneticVariation BEFREE In conclusion, the TERT A1062T variant is an independent negative prognostic factor in younger patients with acute myeloid leukemia and seems to predispose those patients to treatment-related toxicity. 28331964 2017
Leukemia, Myelocytic, Acute
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
0.020 GeneticVariation BEFREE Therefore, molecular testing for TERT A1062T mutation in patients with AML is recommended in order to delineate their prognostic status. 25108601 2014