|
Inflammatory Bowel Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
The CB2-Q63R variant contributes to the risk for pediatric IBD, in particular CD.
|
27875353 |
2019 |
|
Celiac Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
In humans, the nonsynonymous mutation Q63R, the most common variant of the CB2 receptor, has been found to be associated with multiple diseases, including idiopathic arthritis, obesity, and celiac diseases.
|
29694791 |
2018 |
|
Inflammatory Bowel Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
These pilot findings suggest that CB2 Q63R polymorphism does not play a major role in genetic susceptibility to IBD or in its disease phenotypes among Turkish subjects.
|
25599774 |
2014 |
|
Immune thrombocytopenic purpura
|
|
0.020 |
GeneticVariation
|
BEFREE |
There was a significant statistical difference in the distribution of CNR2 Q63R genotypes between chronic ITP patients group and the control groups.
|
23406660 |
2013 |
|
Celiac Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
The Q63R variant, increasing more than six-fold the risk for CD susceptibility, might eventually represent a novel molecular biomarker for CD risk stratification.
|
22465144 |
2012 |
|
Immune thrombocytopenic purpura
|
|
0.020 |
GeneticVariation
|
BEFREE |
We evaluated a common missense variant (CAA/CGG; Q63R) of the gene encoding the cannabinoid receptor type 2 (GeneID 1269) in 190 children with immune thrombocytopenic purpura and 600 healthy controls.
|
21828121 |
2011 |
|
Multiple Sclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
A significant genetic association was observed between Q63R polymorphism and MS.
|
31407233 |
2020 |
|
Crohn Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The CB2-Q63R variant contributes to the risk for pediatric IBD, in particular CD.
|
27875353 |
2019 |
|
Ulcerative Colitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We genotyped 217 pediatric IBD patients [112 Crohn's disease (CD), 105 ulcerative colitis (UC)] and 600 controls for the CB2-Q63R variant by Taqman assay.
|
27875353 |
2019 |
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our preliminary results suggest a role of CB2-Q63R gene polymorphism in the etiology of RA, thus supporting its potential use as a pharmacological target for selective agonists in clinical practice.
|
30032418 |
2018 |
|
HIV Infections
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of the study was to investigate whether the rs35761398 variants of the cannabinoid receptor 2 (CB2) gene may influence the acquisition of HIV infection and the clinical presentation of HIV/hepatitis C virus (HCV) coinfection.
|
29932291 |
2018 |
|
Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In humans, the nonsynonymous mutation Q63R, the most common variant of the CB2 receptor, has been found to be associated with multiple diseases, including idiopathic arthritis, obesity, and celiac diseases.
|
29694791 |
2018 |
|
Acute respiratory tract infection
|
|
0.010 |
GeneticVariation
|
BEFREE |
The CB2 Q63R variation was associated with increased risk of hospitalization in children with ARTI.
|
28992427 |
2018 |
|
HCV coinfection
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of the study was to investigate whether the rs35761398 variants of the cannabinoid receptor 2 (CB2) gene may influence the acquisition of HIV infection and the clinical presentation of HIV/hepatitis C virus (HCV) coinfection.
|
29932291 |
2018 |
|
Polyarticular juvenile idiopathic arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association between cannabinoid receptor type 2 Q63R variant and oligo/polyarticular juvenile idiopathic arthritis.
|
25974389 |
2015 |
|
Hepatitis B, Chronic
|
|
0.010 |
GeneticVariation
|
BEFREE |
The impact of the cannabinoid receptor 2 (CB2) rs35761398 polymorphism on chronic hepatitis B (CHB) was evaluated in 106 consecutive biopsy-proven CHB patients naive for antiviral therapy.
|
25749560 |
2015 |
|
Complete atrioventricular block
|
|
0.010 |
GeneticVariation
|
BEFREE |
The impact of the cannabinoid receptor 2 (CB2) rs35761398 polymorphism on chronic hepatitis B (CHB) was evaluated in 106 consecutive biopsy-proven CHB patients naive for antiviral therapy.
|
25749560 |
2015 |
|
Juvenile arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
A significant difference in genotype distribution of the CB2 Q63R variant (CNR2 rs35761398) between oligo/poly-articular JIA patients and controls was found (p = 0.001).
|
25974389 |
2015 |
|
Pediatric Obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Childhood Obesity and Age at Menarche.
|
26447698 |
2015 |
|
Hepatitis C
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated the effects of CNR2 rs35761398 in patients with hepatitis C virus (HCV) infection.
|
23707465 |
2014 |
|
Eating Disorders
|
|
0.010 |
GeneticVariation
|
BEFREE |
There is an association between the R63Q polymorphism of the CNR2 gene and eating disorders (P = 0.04; Odds ratio 1.24, 95% CI, (1.01-1.53).
|
19768813 |
2010 |
|
Alcoholic Intoxication, Chronic
|
|
0.010 |
GeneticVariation
|
BEFREE |
There is an association between the Q63R polymorphism of the CB2 gene and alcoholism in a Japanese population (P=0.007; odds ratio 1.25, 95% CI, (1.06-1.47)).
|
17189959 |
2007 |