rs3741981, OAS1

N. diseases: 3
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.020 GeneticVariation BEFREE The polymorphism at OAS1 exon 7 rs3741981 might be a potential genetic marker and can be useful in the assessment of liver fibrosis progression and disease outcome in HCV-infected patients. 26505957 2015
Hepatitis C
CUI: C0019196
Disease: Hepatitis C
0.020 GeneticVariation BEFREE Moreover, individuals carrying the A allele in these SNPs exhibited an increased risk for chronic HCV infection (rs2660 and rs10774671: OR = 1.356 [1.051-1.749]; rs3741981: 1.363 [1.085-1.712]). 22710942 2013
Fibrosis, Liver
CUI: C0239946
Disease: Fibrosis, Liver
0.010 GeneticVariation BEFREE The polymorphism at OAS1 exon 7 rs3741981 might be a potential genetic marker and can be useful in the assessment of liver fibrosis progression and disease outcome in HCV-infected patients. 26505957 2015
Rubella
CUI: C0035920
Disease: Rubella
0.010 GeneticVariation BEFREE Importantly, two SNPs (rs3741981 and rs10774670) independently cross-regulated rubella virus-specific IL-10 secretion levels (p < or = 0.031). 20079393 2010