|
Endometriosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
No associations were found with rs3761548 and rs2232366 either for endometriosis-related infertility group or idiopathic infertility group.
|
21481380 |
2011 |
|
Allergic rhinitis (disorder)
|
|
0.030 |
GeneticVariation
|
BEFREE |
The results demonstrated that females homozygous for the rare FOXP3 rs3761548 allele (A/A) are protected against AR; otherwise, females who are either wild types (C/C) or heterozygote carriers (C/A) of the rare allele are more susceptible to AR (OR [95%CI] = 2.089 [1,095; 3.988]).
|
21763379 |
2011 |
|
Allergic rhinitis (disorder)
|
|
0.030 |
GeneticVariation
|
BEFREE |
The diplotype rs3761548-rs4824747 in FOXP3 gene with "AG" was associated with risk of AR (P=0.031, OR=1.755).
|
22836044 |
2012 |
|
Acute Chest Syndrome
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results showed that single nucleotide polymorphism rs3761548 had association with ACS in Chinese Han population.
|
23299803 |
2013 |
|
Vitiligo
|
|
0.020 |
GeneticVariation
|
BEFREE |
The rs3761548 of FOXP3 gene in our population may be associated with susceptibility to vitiligo because of altered expression.
|
23498308 |
2013 |
|
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)
|
|
0.020 |
GeneticVariation
|
BEFREE |
The rs3761548 of FOXP3 gene in our population may be associated with susceptibility to vitiligo because of altered expression.
|
23498308 |
2013 |
|
Autoimmune Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
The rs3761548 polymorphism (-3279 C>A) of FOXP3 gene is associated with several autoimmune disorders.
|
23498308 |
2013 |
|
Vitiligo
|
|
0.020 |
GeneticVariation
|
BEFREE |
Significantly increased vitiligo risk was associated with the rs2232365 GG [odds ratio (OR) 1·68, 95% confidence interval (CI) 1·17-2·39, P = 0·004] and rs3761548 AA (OR 1·82, 95% CI 1·10-3·01, P = 0·033) genotypes compared with the rs2232365 AA and rs3761548 CC genotypes.
|
23582052 |
2013 |
|
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)
|
|
0.020 |
GeneticVariation
|
BEFREE |
Significantly increased vitiligo risk was associated with the rs2232365 GG [odds ratio (OR) 1·68, 95% confidence interval (CI) 1·17-2·39, P = 0·004] and rs3761548 AA (OR 1·82, 95% CI 1·10-3·01, P = 0·033) genotypes compared with the rs2232365 AA and rs3761548 CC genotypes.
|
23582052 |
2013 |
|
Systemic Scleroderma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Single-marker analysis of allelic and genotype frequencies revealed that SNP rs3761548 was not associated with systemic sclerosis susceptibility.
|
23707908 |
2013 |
|
Autoimmune Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
FoxP3 rs3761548 polymorphism predicts autoimmune disease susceptibility: a meta-analysis.
|
23993983 |
2013 |
|
Graves Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Because a single nucleotide polymorphism (SNP) within the FoxP3 gene (rs3761548 in the promoter region) is associated with susceptibility to Graves' disease, this study detected rs3761548 in a hospital-based case-control study.
|
24035934 |
2013 |
|
Non-Small Cell Lung Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The data showed that the A allele of rs3761548 significantly increased NSCLC risk (P=0.000, OR=2.32, 95%CI=1.736-3.102).
|
24035934 |
2013 |
|
Malignant neoplasm of breast
|
|
0.040 |
GeneticVariation
|
BEFREE |
Foxp3 promoter polymorphism (rs3761548) in breast cancer progression: a study from India.
|
24338714 |
2014 |
|
Breast Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Foxp3 promoter polymorphism (rs3761548) in breast cancer progression: a study from India.
|
24338714 |
2014 |
|
Tumor Progression
|
|
0.020 |
GeneticVariation
|
BEFREE |
Stratified data also revealed an association of homozygous mutant genotype with advanced stage of tumor in premenopausal women (OR = 4.56; 95% CI = 1.07-19.38; p = 0.04) with disease duration of <6 months (OR = .10; 95% CI = 1.80-20.50; p = 0.002) suggestive of modulating effect of rs3761548 in tumor progression.
|
24338714 |
2014 |
|
Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
However, with respect to AA genotype of rs3761548, we found highly significant association with the advanced stage (T3-4) of the tumor (OR = 3.90; 95% confidence interval (CI) = 1.56-9.70; p = 0.03).
|
24338714 |
2014 |
|
Triple-Negative Breast Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study aimed to investigate a polymorphism (rs3761548) and the protein expression of FOXP3 for a possible involvement in TNBC susceptibility and prognosis.
|
24877082 |
2014 |
|
Triple Negative Breast Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study aimed to investigate a polymorphism (rs3761548) and the protein expression of FOXP3 for a possible involvement in TNBC susceptibility and prognosis.
|
24877082 |
2014 |
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
The frequencies of AA and AC genotypes at rs3761548 in the FOXP3 gene were significantly higher in MS group as compared with healthy subjects (P < 0.05).
|
25326790 |
2015 |
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Moreover, the A allele of rs3761548 was observed to be associated with higher susceptibility of CRC [OR (95% CI) = 1.792 (1.424-2.254)].
|
25416053 |
2014 |
|
Malignant neoplasm of colon and/or rectum
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of FoxP3 rs3761548 polymorphism with susceptibility to colorectal cancer in the Chinese population.
|
25416053 |
2014 |
|
Hepatic Veno-Occlusive Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, this is the first report on FOXP3 rs3761548 SNP in allo-HSCT and we suggest that this SNP be considered a candidate marker for predicting the development of HVOD and CMV infection after allo-HSCT.
|
26735609 |
2016 |
|
Cytomegalovirus Infections
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, this is the first report on FOXP3 rs3761548 SNP in allo-HSCT and we suggest that this SNP be considered a candidate marker for predicting the development of HVOD and CMV infection after allo-HSCT.
|
26735609 |
2016 |
|
Graft-vs-Host Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, there was no difference in graft-versus-host disease (GVHD) relapse or blood stream infection (BSI), depending on the genotype at rs3761548 locus.
|
26735609 |
2016 |