|
Age related macular degeneration
|
|
0.860 |
GeneticVariation
|
BEFREE |
Among them, CETP (rs3764261/rs2303790) and ABCG1 (rs57137919) were the major susceptibility genes for PCV in Asian population and ABCG1 (rs57137919) showed allelic diversity between PCV and AMD.
|
29977615 |
2018 |
|
Age related macular degeneration
|
|
0.860 |
GeneticVariation
|
BEFREE |
Our study identified two polymorphisms with a higher risk of AMD development (rs5882 and rs708272) and a protective polymorphism for AMD (rs3764261).
|
28918250 |
2017 |
|
Age related macular degeneration
|
|
0.860 |
GeneticVariation
|
BEFREE |
This meta-analysis revealed that both CETP rs3764261 and LIPC rs10468017 polymorphisms were significantly associated with AMD risk.
|
26503844 |
2015 |
|
Age related macular degeneration
|
|
0.860 |
GeneticVariation
|
BEFREE |
Our data suggested that the allele A in rs3764261 in CETP gene may be associated with a decreased risk of advanced AMD in Chinese population.
|
24498989 |
2015 |
|
Age related macular degeneration
|
|
0.860 |
GeneticVariation
|
BEFREE |
The SNP rs3764261 in the cholesteryl ester transfer protein (CETP) gene was associated significantly with neovascular AMD (P = 1.82×10(-4); odds ratio [OR], 1.89) and PCV (P = 4.04×10(-4); OR, 1.80).
|
24393350 |
2014 |
|
Age related macular degeneration
|
|
0.860 |
GeneticVariation
|
BEFREE |
After multivariate adjustment for age, sex, educational level, smoking, BMI, lipid-lowering medication use, cardiovascular disease and diabetes, and for all relevant genetic polymorphisms (ApoE2, ApoE4, CFH Y402H, ARMS2 A69S, LIPC rs10468017, LIPC rs493258, LPL rs12678919, ABCA1 rs1883025 and CETP rs3764261), higher HDL was significantly associated with an increased risk of early (OR = 2.45, 95%CI: 1.54-3.90; P = 0.0002) and any AMD (OR = 2.29, 95%CI: 1.46-3.59; P = 0.0003).
|
24608419 |
2014 |
|
Age related macular degeneration
|
|
0.860 |
GeneticVariation
|
GWASCAT |
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.
|
21665990 |
2011 |
|
Age related macular degeneration
|
|
0.860 |
GeneticVariation
|
GWASDB |
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.
|
21665990 |
2011 |
|
Age related macular degeneration
|
|
0.860 |
GeneticVariation
|
GWASDB |
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.
|
20385819 |
2010 |
|
Metabolic Syndrome X
|
|
0.830 |
GeneticVariation
|
BEFREE |
Our data support the notion that the consumption of a Mediterranean diet may play a contributing role in triggering lipid metabolism by interacting with the rs3764261 SNP at CETP gene locus in MetS patients.
|
28057378 |
2018 |
|
Metabolic Syndrome X
|
|
0.830 |
GeneticVariation
|
BEFREE |
No significant interactions were found between rs3764261 and macronutrient intakes in association with MetS or its components.
|
29942448 |
2018 |
|
Metabolic Syndrome X
|
|
0.830 |
GeneticVariation
|
BEFREE |
(3) The rs1800775 polymorphism was associated with high fasting blood glucose levels and low high density lipoprotein cholesterol (HDL-C); rs3764261 and rs12149545 polymorphisms were associated with all components of MS except high blood pressure; rs711752 and rs708272 polymorphisms were associated with low HDL-C (all <i>p</i> < 0.05).
|
28629169 |
2017 |
|
Metabolic Syndrome X
|
|
0.830 |
GeneticVariation
|
GWASDB |
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
|
21386085 |
2011 |
|
Metabolic Syndrome X
|
|
0.830 |
GeneticVariation
|
GWASCAT |
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.
|
21386085 |
2011 |
|
Metabolic Syndrome X
|
|
0.830 |
GeneticVariation
|
GWASCAT |
A genome-wide association study of the metabolic syndrome in Indian Asian men.
|
20694148 |
2010 |
|
Metabolic Syndrome X
|
|
0.830 |
GeneticVariation
|
GWASDB |
A genome-wide association study of the metabolic syndrome in Indian Asian men.
|
20694148 |
2010 |
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
|
30926973 |
2019 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
We replicated the association of rs3764261 within CETP with HDL-C levels in the study population, and found other previously unidentified SNPs to be significant at the suggestive level, in both previously identified and unidentified genes.
|
31211820 |
2019 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of blood lipids in Indians confirms universality of established variants.
|
30911093 |
2019 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Triglycerides measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |