rs3790843, NR5A2

N. diseases: 7
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Pancreatic carcinoma
CUI: C0235974
Disease: Pancreatic carcinoma
0.020 GeneticVariation BEFREE Our results showed that the rs3790843 (GA vs GG: OR=0.86, CI=0.76-0.98, <i>P</i>=0.992; GA+AA vs GG: OR=0.83, CI=0.73-0.94, <i>P</i>=0.950; A vs G: OR=0.85, CI=0.78-0.93, <i>P</i>=0.802), rs3790844 (CC vs TT: OR=0.65, CI=0.54-0.78, <i>P</i>=0.617; CC vs TT+CT: OR=0.73, CI=0.62-0.85, <i>P</i>=0.742; C vs T: OR=0.78, CI=0.73-0.84, <i>P</i>=0.555) and rs12029406 (TT vs CC: OR=0.73, CI=0.61-0.89, <i>P</i>=0.483; TT vs CC+CT: OR=0.78, CI=0.66-0.92, <i>P</i>=0.648; T vs C: OR=0.87, CI=0.79-0.95, <i>P</i>=0.837) polymorphisms were associated statistically with the risk of pancreatic cancer. 29785120 2018
Malignant neoplasm of pancreas
CUI: C0346647
Disease: Malignant neoplasm of pancreas
0.020 GeneticVariation BEFREE Our results showed that the rs3790843 (GA vs GG: OR=0.86, CI=0.76-0.98, <i>P</i>=0.992; GA+AA vs GG: OR=0.83, CI=0.73-0.94, <i>P</i>=0.950; A vs G: OR=0.85, CI=0.78-0.93, <i>P</i>=0.802), rs3790844 (CC vs TT: OR=0.65, CI=0.54-0.78, <i>P</i>=0.617; CC vs TT+CT: OR=0.73, CI=0.62-0.85, <i>P</i>=0.742; C vs T: OR=0.78, CI=0.73-0.84, <i>P</i>=0.555) and rs12029406 (TT vs CC: OR=0.73, CI=0.61-0.89, <i>P</i>=0.483; TT vs CC+CT: OR=0.78, CI=0.66-0.92, <i>P</i>=0.648; T vs C: OR=0.87, CI=0.79-0.95, <i>P</i>=0.837) polymorphisms were associated statistically with the risk of pancreatic cancer. 29785120 2018
Malignant neoplasm of pancreas
CUI: C0346647
Disease: Malignant neoplasm of pancreas
0.020 GeneticVariation BEFREE Our case-control study found that rs3790843 and rs3790844 in the NR5A2 gene are associated with pancreatic cancer risk in Japanese subjects. 26592175 2015
Pancreatic carcinoma
CUI: C0235974
Disease: Pancreatic carcinoma
0.020 GeneticVariation BEFREE Our case-control study found that rs3790843 and rs3790844 in the NR5A2 gene are associated with pancreatic cancer risk in Japanese subjects. 26592175 2015
Neoplasm Metastasis
CUI: C0027627
Disease: Neoplasm Metastasis
0.010 GeneticVariation BEFREE We found that NR5A2 rs3790843 polymorphism was significantly associated with the risk of GC which had regional lymph node metastasis (p = 0.044) or distant metastasis (p = 0.020). 25514243 2014
Neoplasms
CUI: C0027651
Disease: Neoplasms
0.010 GeneticVariation BEFREE Our results represent the first demonstration that the NR5A2 rs3790844 polymorphism is associated with increased OS of GC patients in the dominant model, and similar results were found among the female group and tumor size >5 cm group for NR5A2 rs3790843 polymorphism. 25514243 2014
Malignant neoplasm of stomach
CUI: C0024623
Disease: Malignant neoplasm of stomach
0.010 GeneticVariation BEFREE We found that NR5A2 rs3790843 polymorphism was significantly associated with the risk of GC which had regional lymph node metastasis (p = 0.044) or distant metastasis (p = 0.020). 25514243 2014
Secondary malignant neoplasm of lymph node
CUI: C0686619
Disease: Secondary malignant neoplasm of lymph node
0.010 GeneticVariation BEFREE We found that NR5A2 rs3790843 polymorphism was significantly associated with the risk of GC which had regional lymph node metastasis (p = 0.044) or distant metastasis (p = 0.020). 25514243 2014
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.010 GeneticVariation BEFREE We found that NR5A2 rs3790843 polymorphism was significantly associated with the risk of GC which had regional lymph node metastasis (p = 0.044) or distant metastasis (p = 0.020). 25514243 2014