rs3894194, GSDMA

N. diseases: 3
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Asthma
CUI: C0004096
Disease: Asthma
0.810 GeneticVariation BEFREE Besides, linear regression analysis showed that rs3894194 and rs12603332 were also significantly associated with asthma phenotypes such as log10 -transformed immunoglobulin E (IgE) level (IU/ml) and log10 -transformed eosinophil percentage (dominant, P=0.04; additive, P=0.01; recessive, P=0.04; recessive, P=0.03; additive, P=0.02). 24649901 2014
Asthma
CUI: C0004096
Disease: Asthma
0.810 GeneticVariation GWASDB Genome-wide association study to identify genetic determinants of severe asthma. 22561531 2012
Asthma
CUI: C0004096
Disease: Asthma
0.810 GeneticVariation GWASDB Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549 2011
Asthma
CUI: C0004096
Disease: Asthma
0.810 GeneticVariation GWASDB Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. 21907864 2011
Asthma
CUI: C0004096
Disease: Asthma
0.810 GeneticVariation GWASDB A large-scale, consortium-based genomewide association study of asthma. 20860503 2010
Asthma
CUI: C0004096
Disease: Asthma
0.810 GeneticVariation GWASCAT A large-scale, consortium-based genomewide association study of asthma. 20860503 2010
Childhood asthma
CUI: C0264408
Disease: Childhood asthma
0.800 GeneticVariation GWASCAT A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. 24241537 2014
Childhood asthma
CUI: C0264408
Disease: Childhood asthma
0.800 GeneticVariation GWASDB Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. 17611496 2007
Systemic Scleroderma
CUI: C0036421
Disease: Systemic Scleroderma
0.710 GeneticVariation BEFREE Our data further establish the link between macrophages and SSc, and suggest that the contribution of the rs3894194 risk variant to SSc susceptibility can be mediated by <i>GSDMA</i> expression in macrophages. 29348297 2018
Systemic Scleroderma
CUI: C0036421
Disease: Systemic Scleroderma
0.710 GeneticVariation GWASCAT Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis. 28314753 2017