|
Ulcerative Colitis
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
|
20228799 |
2010 |
|
Crohn Disease
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
|
Crohn Disease
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
|
Ulcerative Colitis
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
|
20228799 |
2010 |
|
IGA Glomerulonephritis
|
|
0.710 |
GeneticVariation
|
BEFREE |
For additive interaction, the CT or TT of rs</span>4077515 and GG of 17019602 genotype combination conferred a 2.56-fold risk of IgAN reference to CC of 4077515 and AA of 17019602 (OR = 2.56, 95% CI: 0.98-6.69, <i>P</i> = 0.049).
|
29100328 |
2017 |
|
IGA Glomerulonephritis
|
|
0.710 |
GeneticVariation
|
GWASCAT |
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.
|
25305756 |
2014 |
|
Inflammatory Bowel Diseases
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
|
26192919 |
2015 |
|
Ankylosing spondylitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
This case-control study was performed on 349 unrelated AS patients and 469 age- and gender-matched healthy controls, to investigate whether these non-MHC genes (IL1R2 rs2310173, ANTXR2 rs4333130, CARD9 rs4077515, and SNAPC4 rs3812571) influence the AS risk in Iranian population.
|
26590821 |
2016 |
|
Ankylosing spondylitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
A recent genome-wide association screen (GWAS) identified associations (P approximately 0.005) with the non-synonymous single-nucleotide polymorphisms (nsSNPs), rs4077515 and rs3812571, in caspase recruitment domain-containing protein 9 (CARD9) and small nuclear RNA-activating complex polypeptide 4 (SNAPC4) on chromosome 9q that had previously been linked to AS.
|
20463747 |
2010 |
|
Autoimmune thrombocytopenia
|
|
0.010 |
GeneticVariation
|
BEFREE |
A CARD9 single-nucleotide polymorphism rs4077515 is associated with reduced susceptibility to and severity of primary immune thrombocytopenia.
|
31595308 |
2019 |
|
Immune thrombocytopenic purpura
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, CARD9 rs4077515 polymorphism had no effect on corticosteroid sensitivity or refractoriness of IT</span>P.
|
31595308 |
2019 |
|
Thrombocytopenia due to platelet alloimmunization
|
|
0.010 |
GeneticVariation
|
BEFREE |
A CARD9 single-nucleotide polymorphism rs4077515 is associated with reduced susceptibility to and severity of primary immune thrombocytopenia.
|
31595308 |
2019 |
|
Aspergillosis, Allergic Bronchopulmonary
|
|
0.010 |
GeneticVariation
|
BEFREE |
We identified the homozygous CARD9 mutation encoding S12N in patients with allergic bronchopulmonary aspergillosis and revealed activation of RelB and production of IL-5 in peripheral blood mononuclear cells from these patients.
|
29777223 |
2018 |
|
Autoimmune Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The single-nucleotide polymorphism rs4077515 at CARD9 in the human genome, which results in the substitution S12N (CARD9<sup>S12N</sup>), is associated with several autoimmune diseases.
|
29777223 |
2018 |
|
Candidemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
No significant association between the single-nucleotide polymorphisms DECTIN-1 Y238X and CARD9 S12N and the prevalence of candidemia was found, despite the association of the DECTIN-1 238X allele with impaired in vitro and in vivo cytokine production.
|
21881131 |
2011 |