rs657152, ABO

N. diseases: 22
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Thyroid stimulating hormone measurement
0.800 GeneticVariation GWASCAT A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. 23408906 2013
Thyroid stimulating hormone measurement
0.800 GeneticVariation GWASDB A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. 23408906 2013
Hormone measurement
CUI: C0441683
Disease: Hormone measurement
0.700 GeneticVariation GWASCAT A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. 23408906 2013
von Willebrand's factor (lab test)
CUI: C2239219
Disease: von Willebrand's factor (lab test)
0.700 GeneticVariation GWASDB Ischemic stroke is associated with the ABO locus: the EuroCLOT study. 23381943 2013
Alkaline phosphatase measurement
CUI: C0201850
Disease: Alkaline phosphatase measurement
0.700 GeneticVariation GWASCAT Genome-wide association study on serum alkaline phosphatase levels in a Chinese population. 24094242 2013
Activated Partial Thromboplastin Time measurement
0.700 GeneticVariation GWASDB A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the HumanCVD focused genotyping array. 23188048 2013
Serum albumin measurement
CUI: C0523465
Disease: Serum albumin measurement
0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178 2013
Venous Thrombosis
CUI: C0042487
Disease: Venous Thrombosis
0.700 GeneticVariation GWASDB Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis. 22675575 2012
Protein measurement
CUI: C0202202
Disease: Protein measurement
0.700 GeneticVariation GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
Serum total cholesterol measurement
CUI: C1445957
Disease: Serum total cholesterol measurement
0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
Venous Thromboembolism
CUI: C1861172
Disease: Venous Thromboembolism
0.700 GeneticVariation GWASDB A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. 22672568 2012
Duodenal Ulcer
CUI: C0013295
Disease: Duodenal Ulcer
0.700 GeneticVariation GWASDB A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population. 22387998 2012
C-reactive protein measurement
CUI: C0201657
Disease: C-reactive protein measurement
0.700 GeneticVariation GWASDB A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation. 22291609 2012
Soluble Interleukin 6 Receptor Measurement
0.700 GeneticVariation GWASCAT Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. 23251661 2012
Polysomnography
CUI: C0162701
Disease: Polysomnography
0.700 GeneticVariation GWASDB Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. 23251661 2012
Pseudocholinesterase Measurement
CUI: C1168443
Disease: Pseudocholinesterase Measurement
0.700 GeneticVariation GWASDB Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. 21239051 2011
Diabetes Mellitus, Insulin-Dependent
0.700 GeneticVariation GWASCAT Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. 21829393 2011
Autoantibody measurement
CUI: C1272321
Disease: Autoantibody measurement
0.700 GeneticVariation GWASCAT Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. 21829393 2011
Venous Thromboembolism
CUI: C1861172
Disease: Venous Thromboembolism
0.700 GeneticVariation GWASDB Genetics of venous thrombosis: insights from a new genome wide association study. 21980494 2011
Measurement of liver enzyme
CUI: C0428321
Disease: Measurement of liver enzyme
0.700 GeneticVariation GWASDB Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. 18940312 2008
Alkaline phosphatase measurement
CUI: C0201850
Disease: Alkaline phosphatase measurement
0.700 GeneticVariation GWASCAT Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. 18940312 2008
Finding of liver enzyme levels
CUI: C1287351
Disease: Finding of liver enzyme levels
0.700 GeneticVariation GWASDB Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. 18940312 2008
Malignant Neoplasms
CUI: C0006826
Disease: Malignant Neoplasms
0.010 GeneticVariation BEFREE The T alleles of rs495828 and rs657152 were also significantly associated with an elevated cancer risk (adjusted OR = 1.58, 95% CI: 1.17-2.14; adjusted OR = 1.51, 95% CI: 1.09-2.10). 23816557 2014
Primary malignant neoplasm
CUI: C1306459
Disease: Primary malignant neoplasm
0.010 GeneticVariation BEFREE The T alleles of rs495828 and rs657152 were also significantly associated with an elevated cancer risk (adjusted OR = 1.58, 95% CI: 1.17-2.14; adjusted OR = 1.51, 95% CI: 1.09-2.10). 23816557 2014
Coronary Artery Disease
CUI: C1956346
Disease: Coronary Artery Disease
0.010 GeneticVariation BEFREE Alleles of ABCG8 and ABO associated with elevated phytosterol levels displayed significant associations with increased CAD risk (rs4245791 odds ratio, 1.10; 95% CI, 1.06 to 1.14; P=2.2 x 10(-6); rs657152 odds ratio, 1.13; 95% CI, 1.07 to 1.19; P=9.4 x 10(-6)), whereas alleles at ABCG8 associated with reduced phytosterol levels were associated with reduced CAD risk (rs41360247 odds ratio, 0.84; 95% CI, 0.78 to 0.91; P=1.3 x 10(-5)). 20529992 2010