|
Fetal hemoglobin determination
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Original Research: A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease.
|
27022141 |
2016 |
|
Fetal hemoglobin determination
|
|
0.800 |
GeneticVariation
|
GWASDB |
Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans.
|
22936743 |
2012 |
|
Fetal hemoglobin determination
|
|
0.800 |
GeneticVariation
|
GWASDB |
Recently, BCL11A (zinc-finger protein) was identified as a regulator of HbF, and the strongest association signals were observed either directly for rs766432 or for correlated single-nucleotide polymorphisms (SNPs).
|
21326311 |
2011 |
|
Fetal hemoglobin determination
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Recently, BCL11A (zinc-finger protein) was identified as a regulator of HbF, and the strongest association signals were observed either directly for rs766432 or for correlated single-nucleotide polymorphisms (SNPs).
|
21326311 |
2011 |
|
Fetal hemoglobin determination
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association studies also validated a previously identified SNP (rs766432) in BCL11A, a gene known to affect fetal hemoglobin levels (P = 2.6E-21) and in Thailand and Hong Kong subjects.
|
20018918 |
2010 |
|
Fetal hemoglobin determination
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association studies also validated a previously identified SNP (rs766432) in BCL11A, a gene known to affect fetal hemoglobin levels (P = 2.6E-21) and in Thailand and Hong Kong subjects.
|
20018918 |
2010 |
|
Fetal hemoglobin determination
|
|
0.800 |
GeneticVariation
|
GWASDB |
A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.
|
17767159 |
2007 |
|
Reticulocyte count (procedure)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Anemia, Sickle Cell
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The genetics of hemoglobin A2 regulation in sickle cell anemia.
|
25042611 |
2014 |
|
Hemoglobin A2 measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The genetics of hemoglobin A2 regulation in sickle cell anemia.
|
25042611 |
2014 |
|
Anemia, Sickle Cell
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetic determinants of haemolysis in sickle cell anaemia.
|
23406172 |
2013 |
|
Anemia, Sickle Cell
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients.
|
21326311 |
2011 |
|
Hemoglobin E disease
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
|
20183929 |
2010 |
|
Thalassemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
To study the influence of the β globin locus control region (LCR) genotypic background on the phenotype modifying role of BCL11A polymorphisms, 100 cases of thalassemia, 48 homozygous for the A allele and 52 homozygous for the G allele at the 5'HS4-LCR palindromic polymorphic site were genotyped for two BCL11A single nucleotide polymorphisms (rs11886868 and rs766432) in the intronic region of this gene.
|
23541515 |
2013 |