rs916145, USF2

N. diseases: 2
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Biliary Atresia
CUI: C0005411
Disease: Biliary Atresia
0.010 GeneticVariation BEFREE The study demonstrates that C allele of rs916145 in USF2 gene has more frequency for developing BA, and decreased USF2 protein nuclear translocation might partly play a role in the decreased hepcidin expression in the cholestatic liver injury of the late stage of BA. 18970934 2008
Congenital atresia of extrahepatic bile duct
CUI: C4520983
Disease: Congenital atresia of extrahepatic bile duct
0.010 GeneticVariation BEFREE The study demonstrates that C allele of rs916145 in USF2 gene has more frequency for developing BA, and decreased USF2 protein nuclear translocation might partly play a role in the decreased hepcidin expression in the cholestatic liver injury of the late stage of BA. 18970934 2008