|
Kidney Diseases
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies susceptibility loci for IgA nephropathy.
|
21399633 |
2011 |
|
Kidney Diseases
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies susceptibility loci for IgA nephropathy.
|
21399633 |
2011 |
|
IGA Glomerulonephritis
|
|
0.720 |
GeneticVariation
|
BEFREE |
After Cochran-Armitage test for trend analysis, seven IgAN-associated SNPs located in the major histocompatibility complex (MHC) region were found to be significantly associated with the susceptibility of IMN, with rs9275596 as the top one (p = 1.97E-43, OR = 3.977).
|
28929317 |
2017 |
|
IGA Glomerulonephritis
|
|
0.720 |
GeneticVariation
|
BEFREE |
The T allele at rs9275596 was significantly associated with macroscopic haematuria of IgAN patients under the dominant and additive models of inheritance, (P < 0.001, Pc = 0.007, OR = 2.983) and (P < 0.001, Pc = 0.007, OR = 2.17), respectively.
|
27450519 |
2017 |
|
IGA Glomerulonephritis
|
|
0.720 |
GeneticVariation
|
BEFREE |
A combination of the rs2856717T/C, rs9275596C/T, and rs2412971A/G had effects on the susceptibility of IgAN (P = 0.001).
|
27450519 |
2017 |
|
IGA Glomerulonephritis
|
|
0.720 |
GeneticVariation
|
GWASCAT |
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.
|
25305756 |
2014 |
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
|
Allergy to peanuts
|
|
0.020 |
GeneticVariation
|
BEFREE |
Here we conduct the first genome-wide association study of well-defined FA, including specific subtypes (peanut, milk and egg) in 2,759 US participants (1,315 children and 1,444 parents) from the Chicago Food Allergy Study, and identify peanut allergy (PA)-specific loci in the HLA-DR and -DQ gene region at 6p21.32, tagged by rs7192 (P=5.5 × 10(-8)) and rs9275596 (P=6.8 × 10(-10)), in 2,197 participants of European ancestry.
|
25710614 |
2015 |
|
Allergy to peanuts
|
|
0.020 |
GeneticVariation
|
BEFREE |
However, a recent large genomewide association study of patients with peanut allergy and their family members found 2 PA-associated single-nucleotide polymorphisms (rs9275596 and rs7192) mapping to regions involving the HLA-DR and HLA-DQ genes.
|
26522257 |
2015 |
|
Idiopathic Membranous Glomerulonephritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Conditional logistic regression analysis displayed that SNPs protective from IMN (odds ratio < 1.00) were still significantly associated with IMN (p = 3.67E-4 for rs660895 and p = 1.26E-4 for rs9275224) with the most significant SNP rs9275596 as a covariate.
|
28929317 |
2017 |
|
IgE-mediated food allergy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Here we conduct the first genome-wide association study of well-defined FA, including specific subtypes (peanut, milk and egg) in 2,759 US participants (1,315 children and 1,444 parents) from the Chicago Food Allergy Study, and identify peanut allergy (PA)-specific loci in the HLA-DR and -DQ gene region at 6p21.32, tagged by rs7192 (P=5.5 × 10(-8)) and rs9275596 (P=6.8 × 10(-10)), in 2,197 participants of European ancestry.
|
25710614 |
2015 |