Source: GWASDB

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 4 4
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 18 140
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 30 202
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 2 2
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 14 12
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885 9 12
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 7 16
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 3 20
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 13 4
POU5F1 Q01860 POU class 5 homeobox 1 0.95 0.441 0.846 15 14
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846 3 2
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808 6 4
MST1 P26927 macrophage stimulating 1 Enzyme 4.8E-19 0.465 0.885 6 1
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769 11 20
SEMA6A Q9H2E6 semaphorin 6A Signaling 1.00 0.486 0.808 1 1
CYLD Q9NQC7 CYLD lysine 63 deubiquitinase Enzyme 1.00 0.498 0.846 1 7
DAG1 Q14118 dystroglycan 1 Receptor 0.98 0.498 0.808 1 1
TAP1 Q03518 transporter 1, ATP binding cassette subfamily B member Transporter 5.3E-06 0.500 0.808 3 5
RHOA P61586 ras homolog family member A Enzyme modulator 0.60 0.502 0.808 1 2
TYK2 P29597 tyrosine kinase 2 Kinase 4.5E-08 0.505 0.769 8 4
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808 4 6
PSMB9 P28065 proteasome 20S subunit beta 9 2.7E-03 0.514 0.808 4 7
TNFSF15 O95150 TNF superfamily member 15 Signaling 2.8E-03 0.531 0.692 7 10
PTPN2 P17706 protein tyrosine phosphatase non-receptor type 2 1.00 0.538 0.692 12 8