Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 90
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 58
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 40
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 41
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 13
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 54
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923 23
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 45
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 17
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 69
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846 17
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 18
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 31