Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
AZIN1 O14977 antizyme inhibitor 1 Enzyme 0.99 0.716 0.462 2
GRK4 P32298 G protein-coupled receptor kinase 4 Kinase 1.6E-15 0.716 0.500 1
MLLT3 P42568 MLLT3 super elongation complex subunit Nucleic acid binding 1.00 0.674 0.500 1
ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 1.2E-02 0.612 0.538 5
CAPN10 Q9HC96 calpain 10 Enzyme 6.9E-13 0.621 0.577 3
ATP5F1B P06576 ATP synthase F1 subunit beta Transporter 0.98 0.626 0.654 16
GRK2 P25098 G protein-coupled receptor kinase 2 Kinase 1.00 0.532 0.654 15
CASP7 P55210 caspase 7 Enzyme 5.4E-05 0.581 0.654 9
LAMB2 P55268 laminin subunit beta 2 Enzyme modulator 2.5E-19 0.601 0.654 4
GRK6 P43250 G protein-coupled receptor kinase 6 Kinase 4.9E-04 0.670 0.654 3
TRIP10 Q15642 thyroid hormone receptor interactor 10 1.7E-05 0.650 0.654 1
ADORA1 P30542 adenosine A1 receptor G-protein coupled receptor 1.5E-02 0.578 0.692 13
TRPC6 Q9Y210 transient receptor potential cation channel subfamily C member 6 Ion channel 3.0E-07 0.514 0.692 13
UTS2R Q9UKP6 urotensin 2 receptor G-protein coupled receptor 2.3E-05 0.566 0.692 10
HAS2 Q92819 hyaluronan synthase 2 0.99 0.588 0.692 5
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731 13
CCNE1 P24864 cyclin E1 Enzyme modulator 0.97 0.538 0.731 11
C5 P01031 complement C5 Enzyme modulator 8.1E-24 0.550 0.731 8
PAX2 Q02962 paired box 2 0.67 0.495 0.731 6
GRK3 P35626 G protein-coupled receptor kinase 3 Kinase 0.71 0.621 0.731 5
FGF23 Q9GZV9 fibroblast growth factor 23 Signaling 3.1E-02 0.460 0.731 5
SMAD6 O43541 SMAD family member 6 Transcription factor 3.6E-20 0.579 0.731 3
ACVR1 Q04771 activin A receptor type 1 Kinase 0.33 0.535 0.731 2
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 17