Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 241 7
IFNA2 P01563 interferon alpha 2 0.442 0.885 170 0
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923 108 98
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808 74 144
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 66 6
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 61 1
NF2 P35240 neurofibromin 2 1.00 0.468 0.885 54 51
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 52 0
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769 52 34
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 48 17
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808 47 26
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 45 2
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808 37 34
CRYAB P02511 crystallin alpha B 2.2E-02 0.515 0.731 35 16
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808 35 5
KRT8 P05787 keratin 8 2.4E-08 0.517 0.654 35 7
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 34 6
FLCN Q8NFG4 folliculin 0.79 0.537 0.885 30 122
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808 29 42
KEAP1 Q14145 kelch like ECH associated protein 1 3.9E-04 0.475 0.808 29 1
PRAME P78395 preferentially expressed antigen in melanoma 2.4E-07 0.531 0.577 27 0
ANXA4 P09525 annexin A4 1.2E-08 0.599 0.692 26 2