Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 238
IFNA2 P01563 interferon alpha 2 0.442 0.885 169
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168
IFNG P01579 interferon gamma 0.47 0.288 0.962 157
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 96
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 84
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 76
IL2 P60568 interleukin 2 0.48 0.336 0.885 73
CLU P10909 clusterin 7.8E-05 0.426 0.885 65
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 62
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 61
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846 59
IFNB1 P01574 interferon beta 1 0.421 0.846 49
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846 38
PAX6 P26367 paired box 6 1.00 0.450 0.769 37
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808 30
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 27
PRAME P78395 preferentially expressed antigen in melanoma 2.4E-07 0.531 0.577 27
XRCC3 O43542 X-ray repair cross complementing 3 1.9E-10 0.505 0.769 27
IFNA1 P01562 interferon alpha 1 0.371 0.923 24
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 21
CDKN1C P49918 cyclin dependent kinase inhibitor 1C 0.82 0.456 0.846 18
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 18
FAT4 Q6V0I7 FAT atypical cadherin 4 1.00 0.539 0.808 17