Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MIR124-1 microRNA 124-1 0.663 0.500 2
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731 5
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 32
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 94
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885 20
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885 6
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 23
IL3RA P26951 interleukin 3 receptor subunit alpha Signaling 3.0E-27 0.560 0.769 3
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769 6
MSLN Q13421 mesothelin Extracellular structure 5.9E-25 0.525 0.692 10
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846 20
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846 40
CKMT2 P17540 creatine kinase, mitochondrial 2 Kinase 1.6E-17 0.792 0.192 1
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 149
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 27
SLC5A8 Q8N695 solute carrier family 5 member 8 Transporter 5.0E-16 0.615 0.577 8
CHIT1 Q13231 chitinase 1 7.2E-16 0.525 0.692 14
TNFRSF10A O00220 TNF receptor superfamily member 10a 5.1E-15 0.521 0.731 20
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 35
GZMB P10144 granzyme B Enzyme 3.7E-14 0.453 0.808 18
KLRK1 P26718 killer cell lectin like receptor K1 7.0E-14 0.467 0.769 17
HLA-G P17693 major histocompatibility complex, class I, G 1.4E-11 0.461 0.769 46
CD96 P40200 CD96 molecule 1.4E-11 0.592 0.692 1
CSF3R Q99062 colony stimulating factor 3 receptor Signaling 1.5E-10 0.550 0.692 6