Source: BEFREE

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885 396 7
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769 138 4
XRN1 Q8IZH2 5'-3' exoribonuclease 1 1.00 0.716 0.346 20 1
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885 361 4
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846 114 5
NT5C3A Q9H0P0 5'-nucleotidase, cytosolic IIIA Enzyme 1.5E-02 0.593 0.692 73 4
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846 148 8
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769 96 8
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846 236 33
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692 122 11
HTR4 Q13639 5-hydroxytryptamine receptor 4 G-protein coupled receptor 2.5E-02 0.610 0.615 55 8
HTR7 P34969 5-hydroxytryptamine receptor 7 G-protein coupled receptor 4.5E-02 0.592 0.500 66 2
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 196 21
PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Kinase 0.25 0.561 0.808 91 1
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846 118 9
AACS Q86V21 acetoacetyl-CoA synthetase Enzyme 9.1E-17 0.751 0.308 7 0
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692 98 4
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885 324 3
ASCL1 P50553 achaete-scute family bHLH transcription factor 1 Transcription factor 0.68 0.552 0.692 95 0
ASIC1 P78348 acid sensing ion channel subunit 1 Ion channel 0.93 0.653 0.615 45 2
ASIC2 Q16515 acid sensing ion channel subunit 2 Ion channel 1.00 0.653 0.538 33 4
ASIC3 Q9UHC3 acid sensing ion channel subunit 3 Ion channel 3.4E-07 0.663 0.538 50 1
ASIC4 Q96FT7 acid sensing ion channel subunit family member 4 Ion channel 2.9E-03 0.769 0.115 13 0
ACO1 P21399 aconitase 1 Enzyme 3.8E-18 0.628 0.577 40 2