Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846 19
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
CYP4A22 Q5TCH4 cytochrome P450 family 4 subfamily A member 22 Enzyme 1.4E-29 0.931 0.192 2
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 2
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885 12
SLC6A19 Q695T7 solute carrier family 6 member 19 1.8E-24 0.695 0.577 1
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846 38
EPHX2 P34913 epoxide hydrolase 2 Enzyme 1.8E-21 0.568 0.654 7
TBXAS1 P24557 thromboxane A synthase 1 1.4E-20 0.619 0.615 12
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885 6
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885 2
PLCD1 P51178 phospholipase C delta 1 Enzyme 1.7E-19 0.636 0.577 7
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 12
KYNU Q16719 kynureninase Enzyme 4.2E-18 0.617 0.692 1
CYP4F12 Q9HCS2 cytochrome P450 family 4 subfamily F member 12 Enzyme 1.5E-17 0.890 0.154 1
TACR3 P29371 tachykinin receptor 3 G-protein coupled receptor 1.8E-17 0.553 0.769 5
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
RNPEP Q9H4A4 arginyl aminopeptidase 2.6E-17 0.705 0.385 2
FAH P16930 fumarylacetoacetate hydrolase 4.0E-17 0.612 0.538 4
MYH7 P12883 myosin heavy chain 7 4.2E-16 0.516 0.692 8
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
ALOX12 P18054 arachidonate 12-lipoxygenase, 12S type Enzyme 1.4E-15 0.558 0.692 5
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 59
ACSM3 Q53FZ2 acyl-CoA synthetase medium chain family member 3 Enzyme 1.4E-14 0.623 0.615 2