Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 9 7
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 53 31
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 18 12
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 6 3
CXCR2 P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 1.4E-02 0.445 0.923 5 1
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 4 5
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 94 101
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 61 54
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 26 10
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 13 14
ATF3 P18847 activating transcription factor 3 Transcription factor 8.9E-02 0.494 0.885 13 1
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 11 7
GC P02774 GC vitamin D binding protein Transporter 2.7E-11 0.489 0.885 10 9
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 9 7
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 5 2
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 2 2
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 48 44
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 34 1
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846 29 32
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846 18 13
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 12 15
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846 8 6
IL4R P24394 interleukin 4 receptor Receptor 2.3E-04 0.474 0.846 7 7
PLB1 Q6P1J6 phospholipase B1 1.7E-72 0.488 0.846 4 3