Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 138 40
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 98 61
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 95 596
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 60 28
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 57 16
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846 48 17
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 46 64
KMT2C Q8NEZ4 lysine methyltransferase 2C 1.00 0.558 0.692 29 7
FAT4 Q6V0I7 FAT atypical cadherin 4 1.00 0.539 0.808 20 11
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 18 12
PTPRF P10586 protein tyrosine phosphatase receptor type F Enzyme 1.00 0.578 0.615 8 14
SYMPK Q92797 symplekin 1.00 0.700 0.231 4 8
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 99 10
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 31 67
PRPF19 Q9UMS4 pre-mRNA processing factor 19 1.00 0.792 0.346 4 0
RARB P10826 retinoic acid receptor beta Nuclear receptor 1.00 0.478 0.846 37 30
DDB1 Q16531 damage specific DNA binding protein 1 Nucleic acid binding 1.00 0.666 0.577 10 0
PAX6 P26367 paired box 6 1.00 0.450 0.769 55 109
CLCN3 P51790 chloride voltage-gated channel 3 Ion channel 1.00 0.621 0.615 8 2
MTSS1 O43312 MTSS I-BAR domain containing 1 Cellular structure 1.00 0.581 0.654 8 4
SERBP1 Q8NC51 SERPINE1 mRNA binding protein 1 Nucleic acid binding 1.00 0.716 0.385 4 1
DLC1 Q96QB1 DLC1 Rho GTPase activating protein 1.00 0.529 0.731 11 14
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808 47 136
PA2G4 Q9UQ80 proliferation-associated 2G4 1.00 0.617 0.500 4 2